1-(4-nitrophenyl)-N-phenoxyethanimine | 1242078-92-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(4-nitrophenyl)-N-phenoxyethanimine
• CAS: 1242078-92-7
• 化学式: C₁₄H₁₂N₂O₃
• 分子量: 256.261
• InChiKey: HGBNYQNUWHKHHP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  19.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  64.73
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  1-(4-nitrophenyl)-N-phenoxyethanimine 在 盐酸 作用下， 以 1,4-二氧六环 、 乙腈 、 paraffin oil 为溶剂， 反应 24.0h， 以102.9 mg的产率得到2-(4-nitrophenyl)-1-benzofurane
  参考文献：
  名称：

  One-Pot Preparation of 2-Arylbenzofurans from Oximes with Diaryliodonium Triflate

  摘要：

  A variety of 2-arylbenzofurans were obtained in good yields by the O-arylation of oximes with diaryliodonium triflates, followed by the treatment with HCl in dioxane under warming conditions through the [3,3]-sigmatropic reaction. The present reaction is one-pot transition metal-free method for the preparation of various 2-arylbenzofurans from oximes, which are easily available from the reaction of alkyl aryl ketones with hydroxylamine

  DOI：

  10.3987/com-14-13071
• 作为产物：
  描述：

  p-nitroacetophenone oxime 、 二苯基碘三氟甲烷磺酸盐 在 sodium hydride 作用下， 以 乙腈 、 paraffin oil 为溶剂， 反应 2.5h， 生成 1-(4-nitrophenyl)-N-phenoxyethanimine
  参考文献：
  名称：

  One-Pot Preparation of 2-Arylbenzofurans from Oximes with Diaryliodonium Triflate

  摘要：

  A variety of 2-arylbenzofurans were obtained in good yields by the O-arylation of oximes with diaryliodonium triflates, followed by the treatment with HCl in dioxane under warming conditions through the [3,3]-sigmatropic reaction. The present reaction is one-pot transition metal-free method for the preparation of various 2-arylbenzofurans from oximes, which are easily available from the reaction of alkyl aryl ketones with hydroxylamine

  DOI：

  10.3987/com-14-13071

文献信息

• Polymer-supported copper complex for the direct synthesis of O-aryloxime ethers via cross-coupling of oximes and arylboronic acids
  作者：Liang Wang、Chengyan Huang、Chun Cai

  DOI：10.1016/j.catcom.2009.12.012

  日期：2010.2

  L-proline functionalized chloroacetylated polystyrene supported copper (II) complex was prepared and found to be effective for the cross-coupling reaction between aromatic oximes and arylboronic acids under mild conditions. Only catalytic amount of catalyst was required and no deoximation occurred. The catalyst could be recovered by simple filtration and reused several times without significant loss of activity. (C) 2009 Elsevier B.V. All rights reserved.