4-(di-prop-2-ynylamino)-benzoic acid | 91718-51-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(di-prop-2-ynylamino)-benzoic acid
• 英文别名: 4-(Di-prop-2-inylamino)-benzoesaeure；4-Dipropargylaminobenzoic acid；4-[bis(prop-2-ynyl)amino]benzoic acid
• CAS: 91718-51-3
• 化学式: C₁₃H₁₁NO₂
• 分子量: 213.236
• InChiKey: RCNZDRFWTAOSLV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-溴丙炔 、 alkaline earth salt of/the/ methylsulfuric acid 在 碳酸氢钠 作用下， 生成 4-(di-prop-2-ynylamino)-benzoic acid
  参考文献：
  名称：

  Wolf, Justus Liebigs Annalen der Chemie, 1952, vol. 576, p. 35,41

  摘要：

  DOI：

文献信息

• Heterobifunctional poly(ethyleneglycol) containing acid-labile amino protecting groups and uses thereof
  申请人：Breitenkamp Kurt

  公开号：US20080188638A1

  公开（公告）日：2008-08-07

  The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.

  本发明提供了双功能聚合物，其制备方法以及中间体。这些化合物在各种应用中都有用，包括对生物活性分子进行聚乙二醇化。本发明还提供了使用这些化合物和其组成物的方法。
• POLY(ETHYLENE GLYCOL) DERIVATIVES FOR CLICK CHEMISTRY
  申请人：Sill Kevin

  公开号：US20130178600A1

  公开（公告）日：2013-07-11

  The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.

  本发明提供了双功能聚合物，其制备方法及其中间体。这些化合物在各种应用中都很有用，包括对生物活性分子进行聚乙二醇化。本发明还提供了使用上述化合物及其组合物的方法。
• Poly(ethylene glycol) containing chemically disparate endgroups
  申请人：Breitenkamp Kurt

  公开号：US20080207913A1

  公开（公告）日：2008-08-28

  The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
• POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS
  申请人：Breitenkamp Kurt

  公开号：US20100160645A1

  公开（公告）日：2010-06-24

  The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
• POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS
  申请人：Breitenkamp Kurt

  公开号：US20100280252A1

  公开（公告）日：2010-11-04

  The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.