[2-hydroxy-1-(4-methylphenyl)ethyl] acetate | 98750-12-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2-hydroxy-1-(4-methylphenyl)ethyl] acetate
• CAS: 98750-12-0
• 化学式: C₁₁H₁₄O₃
• 分子量: 194.23
• InChiKey: IHCMQKKDAVRBJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.59
• 重原子数：
  14.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  46.53
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  Alpha-甲基苯乙烯 、 cobalt(III) acetate 生成 [2-hydroxy-1-(4-methylphenyl)ethyl] acetate
  参考文献：
  名称：

  HIRANO, MASAO;MORIMOTO, TAKASHI, J. CHEM. SOC. PERKIN TRANS., 1984, N 6, 1033-1036

  摘要：

  DOI：

文献信息

• Oxidation by cobalt(III) acetate. Part 6. A novel synthesis of the glycol monoacetates from aromatic olefins in wet acetic acid
  作者：Masao Hirano、Takashi Morimoto

  DOI：10.1039/p29840001033

  日期：——

  Oxidation of various aryl-conjugated olefins with cobalt(III) acetate in wet acetic acid under nitrogen affords the glycol monoacetates in moderate to good yields. None of the phenyl rearrangement product is formed in the present reactions. These results are best interpreted by assuming the formation of a Co-co-ordinated intermediate.

  在湿乙酸中，在氮气下用乙酸钴（III）在乙酸中氧化各种芳基共轭烯烃，可得到中等收率的乙二醇单乙酸酯。在本反应中没有形成苯基重排产物。通过假设形成一个协同中间体，可以最好地解释这些结果。
• Bis(NHC)-Palladium(II) Complex-Catalyzed Dioxygenation of Alkenes
  作者：Wenfeng Wang、Feijun Wang、Min Shi

  DOI：10.1021/om900975a

  日期：2010.2.22

  Bis(NHC)-Pd(II) complexes derived from 1,1'-binaphthyl-2,2'-diamine (BINAM) were successfully first used to catalyze the dioxygenation of alkenes under mild conditions tolerant of air and moisture. Cationic NHC-Pd2+ diaquo complex le showed the highest catalytic activity to give 1,2-dioxygenation products with good syn-diastercoselectivity for 1,2-disubstituted alkenes.
• Norman, Julie A.; Thomas, C. Barry; Burrow, Michael J., Journal of the Chemical Society. Perkin transactions I, 1985, p. 1087 - 1094
  作者：Norman, Julie A.、Thomas, C. Barry、Burrow, Michael J.

  DOI：——

  日期：——
• NORMAN, J. A.;THOMAS, C. B.;BURROW, M. J., J. CHEM. SOC. PERKIN TRANS., 1985, N 5, 1087-1093
  作者：NORMAN, J. A.、THOMAS, C. B.、BURROW, M. J.

  DOI：——

  日期：——