4-hydroxy-2,3-dimethoxy-benzoic acid | 116530-58-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-hydroxy-2,3-dimethoxy-benzoic acid
• 英文别名: 4-Hydroxy-2,3-dimethoxy-benzoesaeure；4-Oxy-2.3-dimethoxy-benzoesaeure；2,3-Dimethoxy-4-hydroxy-benzoesaeure；Hydroxy-dimethoxy benzoic acid；4-hydroxy-2,3-dimethoxybenzoic acid
• CAS: 116530-58-6
• 化学式: C₉H₁₀O₅
• 分子量: 198.175
• InChiKey: CHHQEMBTCQDAHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-hydroxy-2,3-dimethoxy-benzoic acid 在 盐酸 、 lithium aluminium tetrahydride 、 potassium carbonate 、 potassium iodide 作用下， 生成 2.3-Dimethoxy-4-benzyloxy-benzylalkohol
  参考文献：
  名称：

  Synthesis of 11-hydroxy-2,3,9,10-tetramethoxy-5,6,13a-tetrahydro-8H-dibenzo[a,g]quinolizine. Structure of stepharotine

  摘要：

  DOI：

  10.1021/jo01257a032
• 作为产物：
  描述：

  4-benzoyloxy-2,3-dimethoxy-benzoic acid methyl ester 在 sodium hydroxide 作用下， 生成 4-hydroxy-2,3-dimethoxy-benzoic acid
  参考文献：
  名称：

  Pacsu, Chemische Berichte, 1923, vol. 56, p. 414

  摘要：

  DOI：

文献信息

• Continuous Method For Producing Amides Of Aromatic Carboxylic Acids
  申请人：Krull Matthias

  公开号：US20120095238A1

  公开（公告）日：2012-04-19

  The invention relates to a continuous method for producing amides of aromatic carboxylic acids by reacting at least one carbonic acid ester of formula (I) R 3 —OOOR 4 , wherein R 3 represents an optionally substituted aromatic hydrocarbon group with 5 to 100 carbon atoms and R 4 represents a hydrocarbon group with 1 to 30 carbon atoms, with at least one amine of formula (II) HNR 1 R 2 , wherein R 1 and R 2 independently represent hydrogen or a hydrocarbon group with 1 to 100 C atoms, in a reaction tube the longitudinal axis of which extends in the direction of propagation of the microwaves of a monomode microwave applicator, under microwave irradiation to form carboxamide.

  该发明涉及一种连续方法，通过在至少一种具有式(I) R3—OOOR4的碳酸酯中，其中R3代表一个具有5至100个碳原子的可选择取代的芳香烃基，R4代表一个具有1至30个碳原子的碳氢基团，与至少一种具有式(II) HNR1R2的胺反应，其中R1和R2独立地代表氢或具有1至100个C原子的碳氢基团，在一个反应管中，在单模微波应用器的微波传播方向上的纵轴下，通过微波辐射形成羧酰胺。
• Method For Producing Amides In The Presence Of Superheated Water
  申请人：Krull Matthias

  公开号：US20110089021A1

  公开（公告）日：2011-04-21

  The invention relates to a method for producing carboxylic acid amides, according to which at least one carboxylic acid of formula (I) R 3 —COON   (I) wherein R 3 is hydrogen or an optionally substituted hydrocarbon radical comprising between 1 and 50 carbon atoms, is reacted with at least one amine of formula (II) HNR 1 R 2 (II) wherein R 1 and R 2 are independently hydrogen or an optionally substituted hydrocarbon radical comprising between 1 and 100 C atoms, to form an ammonium salt, and said ammonium salt is reacted in the presence of superheated water, under microwave irradiation, to form a carboxylic acid amide.

  该发明涉及一种生产羧酸酰胺的方法，根据该方法，至少一种具有以下结构的羧酸（I）R3—COON（I）其中R3是氢或含有1至50个碳原子的可选择取代的烃基，与至少一种具有以下结构的胺（II）HNR1R2（II）其中R1和R2独立地是氢或含有1至100个碳原子的可选择取代的烃基，反应形成一种铵盐，然后在超热水存在下，在微波辐射下，将该铵盐反应形成一种羧酸酰胺。
• [EN] COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES<br/>[FR] SELS DE CUIVRE D'ACIDES ORGANIQUES ET LEUR UTILISATION EN TANT QUE FONGICIDE
  申请人：ISAGRO SPA

  公开号：WO2004103074A1

  公开（公告）日：2004-12-02

  Compounds are described, having general formula (I): A . Cu wherein A represents the bibasic ion of an organic acid which can have the meanings (A1) - (A8) and Cu represents the copper 2+ ion; and the use of compounds having formula (I), individually or in a mixture, for the control of bacterial and fungal phytopathogens on vegetables or parts thereof.

  化合物被描述为具有一般式（I）：A . Cu，其中A代表有机酸的二元离子，可以具有意义（A1）-（A8），Cu代表铜2+离子；以及使用具有式（I）的化合物，单独或混合使用，用于控制蔬菜或其部分上的细菌和真菌植物病原体。
• Continuous Method For Producing Amides of Aromatic Carboxylic Acids
  申请人：Krull Matthias

  公开号：US20110089019A1

  公开（公告）日：2011-04-21

  The invention relates to a continuous method for producing amides of aromatic carboxylic acids, according to which at least one aromatic carboxylic acid of formula (I) Ar—COON   (I) wherein Ar is an optionally substituted aryl radical comprising between 5 and 50 atoms, is reacted with at least one amine of formula (II) HNR 1 R 2 (II) wherein R 1 and R 2 are independently hydrogen or a hydrocarbon radical comprising between 1 and 100 C atoms, to form an ammonium salt, and said ammonium salt is then reacted to form a carboxylic acid amide, under microwave irradiation in a reaction pipe, the longitudinal axis of the pipe being oriented in the direction of propagation of the microwaves of a monomode microwave applicator.

  该发明涉及一种连续生产芳香羧酸酰胺的方法，根据该方法，将式(I)Ar—COON中的至少一种芳香羧酸（其中Ar是一个可选择取代的含有5至50个原子的芳基基团）与式(II)HNR1R2中的至少一种胺（其中R1和R2独立地是氢或含有1至100个碳原子的烃基团）反应，形成铵盐，然后将所述铵盐反应形成羧酸酰胺，在一个反应管中通过微波辐射，管的纵轴沿着单模微波应用器的微波传播方向定向。
• Continuous Method For Producing Esters Of Aromatic Carboxylic Acids
  申请人：Krull Matthias

  公开号：US20120088918A1

  公开（公告）日：2012-04-12

  The invention relates to a continuous method for producing aromatic carboxylic acid esters by reacting at least one aromatic carboxylic acid of formula (I) Ar—COOH (I), wherein Ar represents an optionally substituted aryl group with 5 to 50 atoms, with at least one alcohol of formula (II) R 2 —(OH) n (II), wherein R 2 represents an optionally substituted hydrocarbon group with 1 to 100 C atoms and n is an integer from 1 to 10, in the presence of at least one transesterification catalyst in a reaction tube, the longitudinal axis of which extends in the direction of propagation of the microwaves of a monomode microwave applicator, under microwave irradiation to form the ester.

  本发明涉及一种连续生产芳香羧酸酯的方法，该方法通过在反应管中，在至少一种芳香羧酸(I) Ar-COOH(I)（其中Ar代表具有5至50个原子的可选取代芳基基团）和至少一种醇(II) R2-(OH)n(II)（其中R2代表具有1至100个C原子的可选取代的烃基团，n为1至10的整数）的存在下，在至少一种酯交换催化剂的作用下，在单模微波应用器的微波传播方向上，通过微波辐射形成酯。