3''-Methoxy-4-methyl-[1,1':3',1'']terphenyl-5'-carboxylic acid (6-methyl-pyridin-3-ylmethyl)-amide | 1217483-57-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3''-Methoxy-4-methyl-[1,1':3',1'']terphenyl-5'-carboxylic acid (6-methyl-pyridin-3-ylmethyl)-amide
• 英文别名: 3-(3-methoxyphenyl)-5-(4-methylphenyl)-N-[(6-methylpyridin-3-yl)methyl]benzamide
• CAS: 1217483-57-2
• 化学式: C₂₈H₂₆N₂O₂
• 分子量: 422.527
• InChiKey: RQXOIHKYMUMAAI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  51.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF
  申请人：Wei Zhi-Liang

  公开号：US20110237578A1

  公开（公告）日：2011-09-29

  Compounds are provided according to formula (I), where A, B, W, X′, L, R 1 , R 3 , R 4b , and m′ are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.

  根据公式（I）提供化合物，其中A、B、W、X'、L、R1、R3、R4b和m'的定义如本文所述。所提供的化合物及其制药组合物对哺乳动物包括人类的多种疾病预防和治疗有用，包括但不限于疼痛、炎症、认知障碍、焦虑、抑郁等。
• US9133122B2
  申请人：——

  公开号：US9133122B2

  公开（公告）日：2015-09-15
• [EN] AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSÉS AMIDES, COMPOSITIONS ET UTILISATIONS DES COMPOSÉS ET COMPOSITIONS
  申请人：RENOVIS INC

  公开号：WO2010033168A2

  公开（公告）日：2010-03-25

  Compounds are provided according to formula (I), where A, B, W, X', L, R1, R3, R4b, and m' are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.