α-{[(methylsulfonyl)oxy]imino}-benzeneacetonitrile | 68272-53-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: α-{[(methylsulfonyl)oxy]imino}-benzeneacetonitrile
• 英文别名: α-(methylsulfonyloxyimino)-phenylacetonitrile；α-(methylsulfonyloxyimino)benzyl cyanide；[(Z)-[cyano(phenyl)methylidene]amino] methanesulfonate
• CAS: 68272-53-7
• 化学式: C₉H₈N₂O₃S
• 分子量: 224.24
• InChiKey: XDHUWCBFSRIEEC-PKNBQFBNSA-N

物化性质

• 沸点：
  350.5±25.0 °C(Predicted)
• 密度：
  1.27±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  87.9
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• [EN] SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONISTS<br/>[FR] AGONISTES DES RÉCEPTEURS SPHINGOSINE-1-PHOSPHATE
  申请人：BRISTOL MYERS SQUIBB CO

  公开号：WO2011017578A1

  公开（公告）日：2011-02-10

  Disclosed are compounds of Formula (I), or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein: A is formula (II) Q is a substituted 5-membered monocyclic heteroaryl group; W is CH2, O, or NH; and R1, R2, R3, R4, R5, R6, m, n, t, and x are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.

  揭示了Formula (I)的化合物，或其立体异构体或药用可接受的盐，其中：A为Formula (II)，Q为取代的5-成员单环杂芳基团；W为CH2、O或NH；而R1、R2、R3、R4、R5、R6、m、n、t和x在此处有定义。还揭示了将这些化合物用作G蛋白偶联受体S1P1的选择性激动剂的方法，以及包含这些化合物的药物组合物。这些化合物在治疗、预防或减缓多种治疗领域的疾病或紊乱方面具有用处，如自身免疫疾病和血管疾病。
• RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYPHENOLIC COMPOUND FOR USE IN THE COMPOSITION, AND ALCOHOLIC COMPOUND THAT CAN BE DERIVED THEREFROM
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：US20160145231A1

  公开（公告）日：2016-05-26

  A resist composition containing a compound represented by the general formula (1) or (2), a method for forming a resist pattern using the composition, a polyphenolic compound for use in the composition, and an alcoholic compound that can be derived therefrom are described.

  描述了一种包含由通式（1）或（2）表示的化合物的光刻胶组合物，使用该组合物形成光刻胶图案的方法，用于该组合物的多酚化合物，以及可以由其衍生的醇化合物。
• OPTICAL COMPONENT FORMING COMPOSITION AND CURED PRODUCT THEREOF
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：US20200262787A1

  公开（公告）日：2020-08-20

  The present invention provides an optical component forming composition comprising a tellurium-containing compound or a tellurium-containing resin.

  本发明提供了一种包括含碲化合物或含碲树脂的光学元件成型组合物。
• Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity
  申请人：——

  公开号：US20040013974A1

  公开（公告）日：2004-01-22

  The invention describes the use of oxime alkyl sulfonate compounds of formula 1 1 R 0 is either an R 1 —X group or R 2 ; X is a direct bond, an oxygen atom or a sulfur atom; R 1 is hydrogen, C 1 -C 4 alkyl or a phenyl group which is unsubstituted or substituted by a substituent selected from the group consisting of chloro, bromo, C 1 -C 4 alkyl and C 1 -C 4 -alkyloxy; R 2 is hydrogen or C 1 -C 4 alkyl; and R 3 is straight-chain or branched C 1 -C 12 alkyl which is unsubstituted or substituted by one or more than one halogen atom; as photosensitive add generator in a chemically amplified photoresist which is developable in alkaline medium and which is sensitive to radiation at a wavelength of 340 to 390 nanometers and correspondingly composed positive and negative photoresists for the above-mentioned wavelength range.

  该发明描述了氧肟烷磺酸酯化合物的使用，其化学式为11R0，其中R0是R1—X基团或R2；X是一个直接键，一个氧原子或一个硫原子；R1是氢，C1-C4烷基或苯基，未取代或取代，取代基选择自氯、溴、C1-C4烷基和C1-C4-烷氧基组成的组；R2是氢或C1-C4烷基；R3是直链或支链的C1-C12烷基，未取代或取代，取代一个或多个卤素原子；作为化学增感光阻剂中的光敏添加剂，该增感光阻剂可在碱性介质中显影，对波长为340至390纳米的辐射敏感，相应地组成了上述波长范围内的正负光刻胶。
• RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, POLYMERIC COMPOUND, AND COMPOUND
  申请人：Dazai Takahiro

  公开号：US20100178609A1

  公开（公告）日：2010-07-15

  A resist composition including a base component (A) which exhibits changed solubility in an alkali developing solution under action of an acid, and an acid generator component (B), wherein the base component (A) includes a polymeric compound (A0) containing a structural unit (a0) represented by the general formula (a0-1) shown below: (wherein, R 1 represents a hydrogen atom, an alkyl group or a halogenated alkyl group; R 2 represents a bivalent linking group containing at least one kind of polar groups selected from the group consisting of —O—, —C(═O)—, —C(═O)—O—, a carbonate linkage (—O—C(═O)—O—), —S—, —S(═O) 2 —, —S(═O) 2 —O—, —NH—, —NR 04 — (wherein, R 04 represents an alkyl group or an acyl group), and —NH—C(═O)—; and R 3 represents a cyclic group containing a sulfonyl group within the ring skeleton).

  一种抗蚀组合物，包括一种基础组分（A）和一种酸发生器组分（B），其中基础组分（A）在酸的作用下在碱性显影液中表现出改变的溶解度，基础组分（A）包括一种聚合物化合物（A0），其含有由下式（a0-1）表示的结构单元（a0）：（其中，R1表示氢原子、烷基或卤代烷基；R2表示至少包含一种来自羟基、酰基、碳酸酯键（—O—C（═O）—O—）、碳酰基（—C（═O）—）、磺酰基、磺酰基氧、氨基、取代基为烷基或酰基的氮原子和氨基甲酰的偶联基的双价连接基；R3表示环状基团，其在环骨架内含有磺酰基）。