1-amino-9,10-dihydro-9,10-dioxo-4-[(3-{[2-(sulfooxy)ethyl]sulfonyl}phenyl)amino]-2-anthracenesulfonic acid | 6522-88-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1-amino-9,10-dihydro-9,10-dioxo-4-[(3-{[2-(sulfooxy)ethyl]sulfonyl}phenyl)amino]-2-anthracenesulfonic acid
• 英文别名: 2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4-((3-((2-(sulfooxy)ethyl)sulfonyl)phenyl)amino)-；1-amino-9,10-dioxo-4-[3-(2-sulfooxyethylsulfonyl)anilino]anthracene-2-sulfonic acid
• CAS: 6522-88-9
• 化学式: C₂₂H₁₈N₂O₁₁S₃
• 分子量: 582.59
• InChiKey: VGPIJNLQDSYRBZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  38
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  249
• 氢给体数：
  4
• 氢受体数：
  13

反应信息

• 作为产物：
  描述：

  间-β-羟乙基砜硫酸酯苯胺 、 溴氨酸 在 碳酸氢钠 、 铜 、 copper(l) chloride 作用下， 以 水 为溶剂， 反应 17.0h， 生成 1-amino-9,10-dihydro-9,10-dioxo-4-[(3-{[2-(sulfooxy)ethyl]sulfonyl}phenyl)amino]-2-anthracenesulfonic acid
  参考文献：
  名称：

  반응성 청색 염료 조성물

  摘要：

  这项发明涉及一种混合了10-30重量部的通式（I）化合物和70-90重量部的通式（II）化合物的蓝色染料组合物。 ..........（I）...........（II）

  公开号：

  KR101565868B1

文献信息

• BAIT CHEMISTRIES IN HYDROGEL PARTICLES FOR SERUM BIOMARKER ANALYSIS
  申请人：Liotta Lance

  公开号：US20120107959A1

  公开（公告）日：2012-05-03

  This invention describes the identification of novel organic dye chemistries that can be used as affinity baits to capture proteins and other biomolecules useful in the fields of medical diagnostics, environmental science, toxicology, and infectious disease. Incorporation of unique affinity dye compounds within hydrogel capture particles improves analyte yield and preanalytical precision, and stabilizes the analyte against degradation, while increasing measurement sensitivity. The particles in this invention can be used for routine clinical testing as well as for discovery of low abundance disease biomarkers. Example hydrogel particles containing new high affinity bait chemistries were used to identify a new set of human serum biomarkers.

  本发明描述了识别新有机染料化学结构的方法，这些染料可以用作亲和诱饵，用于捕获在医学诊断、环境科学、毒理学和传染病等领域中有用的蛋白质和其他生物分子。在水凝胶捕获颗粒中加入独特的亲和染料化合物可提高分析物产量和前分析精度，并稳定分析物以防止降解，同时提高测量灵敏度。本发明中的颗粒可用于常规临床测试以及发现低丰度疾病生物标志物。例如，含有新的高亲和力诱饵化学结构的水凝胶颗粒被用于鉴定一组新的人血清生物标志物。
• CHARGED PARTICLES
  申请人：Hayoz Pascal

  公开号：US20120229884A1

  公开（公告）日：2012-09-13

  Disclosed is a composition comprising a charged particle of volume 5 nm 3 to 50 million nm 3 preferably having an inorganic core of SiO 2 , AI 2 O 3 , and/or TiO 2 , or a core essentially consisting of an organic pigment and/or pigment derivative, and a counter ion which is separable from the particle and is not covalently linked to the particle, said counter ion comprising a silicon atom which is directly bound to a carbon atom. Preferably, said charged particle comprises a dye attached to said inorganic core and said counter ion comprises a (poly)siloxane moiety linked via suitable bridge members to a quaternary, positively charged, nitrogen or phosphorus atom, or to a moiety carrying an anionic functional group. Said composition may be used e.g. in the form of a homogenous dispersion in an electrophoretic display.

  本发明涉及一种组合物，包括一个带电粒子，其体积为5nm3至50百万nm3，优选具有SiO2、AI2O3和/或TiO2的无机核心，或者基本上由有机颜料和/或颜料衍生物组成的核心，以及一种可与粒子分离且不与粒子共价连接的对离子，所述对离子包括直接与碳原子结合的硅原子。优选地，所述带电粒子包括连接到所述无机核心的染料，所述对离子包括通过适当的桥连成员连接到四价、带正电的氮或磷原子，或连接到带有负离性官能团的基团上的（聚）硅氧烷基团。所述组合物可以以均匀分散的形式用于电泳显示。
• Binding domain mapping
  申请人：George Mason Research Foundation, Inc.

  公开号：US10126304B2

  公开（公告）日：2018-11-13

  The present disclosure relates to compositions and methodology for revealing binding sites between proteins, proteins and nucleic acids, or proteins and small molecules. The disclosure provides rapid and direct positive identification and sequencing of the contact region between such molecules, and can be applied to individual interacting pairs, as well as large-scale or global interactions.

  本公开涉及用于揭示蛋白质、蛋白质与核酸或蛋白质与小分子之间结合位点的组合物和方法。本发明可对这些分子之间的接触区进行快速、直接的阳性鉴定和测序，并可应用于单个相互作用对以及大规模或全局相互作用。
• ANTHRAPYRIDONE SULPHONIC ACID COMPOUNDS, PREPARATION AND USE THEREOF
  申请人：Dalian University of Technology

  公开号：EP2546309B1

  公开（公告）日：2016-06-01
• ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0525073A1

  公开（公告）日：1993-02-03