[2-(12,14-Dioxa-13-phosphapentacyclo[13.8.0.02,11.03,8.018,23]tricosa-1(15),2(11),3,5,7,9,16,18,20,22-decaen-13-yloxy)phenyl]-diphenylphosphane | 147582-81-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2-(12,14-Dioxa-13-phosphapentacyclo[13.8.0.02,11.03,8.018,23]tricosa-1(15),2(11),3,5,7,9,16,18,20,22-decaen-13-yloxy)phenyl]-diphenylphosphane
• CAS: 147582-81-8
• 化学式: C₃₈H₂₆O₃P₂
• 分子量: 592.57
• InChiKey: JBHRTMOCKAKJAJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.4
• 重原子数：
  43
• 可旋转键数：
  5
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  {Pt(norbornene)3} 、 [2-(12,14-Dioxa-13-phosphapentacyclo[13.8.0.02,11.03,8.018,23]tricosa-1(15),2(11),3,5,7,9,16,18,20,22-decaen-13-yloxy)phenyl]-diphenylphosphane 以 not given 为溶剂， 生成
  参考文献：
  名称：

  A tetraphos ligand with C3 symmetry

  摘要：

  描述了一种具有 C3 对称性的光学活性四磷配体及其铂(0)配位化学。

  DOI：

  10.1039/c39930000314
• 作为产物：
  描述：

  (2-羟基苯基)二苯基膦 、 (R)-(1,1′-联萘-2,2′-二氧)氯膦 在 三乙胺 作用下， 生成 [2-(12,14-Dioxa-13-phosphapentacyclo[13.8.0.02,11.03,8.018,23]tricosa-1(15),2(11),3,5,7,9,16,18,20,22-decaen-13-yloxy)phenyl]-diphenylphosphane
  参考文献：
  名称：

  A tetraphos ligand with C3 symmetry

  摘要：

  描述了一种具有 C3 对称性的光学活性四磷配体及其铂(0)配位化学。

  DOI：

  10.1039/c39930000314

文献信息

• Diphosphorus Ligands Containing a P‐Stereogenic Phosphane and a Chiral Phosphite or Phosphorodiamidite – Evaluation in Pd‐Catalysed Asymmetric Allylic Substitution Reactions
  作者：Pau Clavero、Arnald Grabulosa、Mercè Rocamora、Guillermo Muller、Mercè Font‐Bardia

  DOI：10.1002/ejic.201600550

  日期：2016.9

  derived from both enantiomers of 1,1′-bi-2-naphthol (5–9) and the chlorodiazaphosphepine derived from both enantiomers of N,N′-dimethyl-1,1′-binaphthyl-2,2′-diamine (10–14) in the presence of a base. With these ligands, cationic Pd complexes of the type [Pd(η3-C4H7)(PP′)]PF6 (Pd1–Pd14) were obtained and characterised; the crystal structures of Pd1, Pd2 and Pd13 were obtained. In solution, the complexes

  报道了 14 种新的光学纯 C1 对称磷烷 - 次膦酸盐 (1-4)、磷烷 - 亚磷酸盐 (5-9) 和磷烷 - 亚磷酰胺 (10-14) 配体的合成。配体是通过 (2-羟基苯基) 苯基膦 PPh(2-PhOH)R（R = Me、tBu 和 Ph）与氯二异丙基膦（1 和 2）、氯二苯基膦（3 和 4）缩合制备的，氯代二氧膦衍生自两者1,1'-bi-2-naphthol (5-9) 的对映异构体和衍生自 N,N'-dimethyl-1,1'-binaphthyl-2,2'-diamine (10-14) 的两种对映异构体的氯代二氮杂膦在有基地的情况下。使用这些配体，获得并表征了 [Pd(η3-C4H7)(PP')]PF6 (Pd1–Pd14) 类型的阳离子 Pd 配合物；得到了Pd1、Pd2和Pd13的晶体结构。在解决方案中，由于配体缺乏对称性和甲代烯丙基的存在，复合物以两种非对映异构体的混合物形式存在。Pd
• Synthesis, Characterization, and Reactivity of Ruthenium Bis-Allyl Complexes with Chiral Phosphine-Phosphite Ligands
  作者：Mónica Vaquero、Sergio Vargas、Andrés Suárez、Sergio E. Garcı́a-Garrido、Eleuterio Álvarez、Manuel Mancera、Antonio Pizzano

  DOI：10.1021/om300018s

  日期：2012.5.14

  A series of ruthenium bis-allyl complexes of formula Ru(eta(3)-2-MeC3H4)(2)(P-OP) (I) which incorporate chiral phosphine-phosphite ligands (P-OP) have been prepared and characterized. Compounds I exist in solution as a mixture of two diastereomers (maj and min) differing in the configuration at the metal. Both isomers are in equilibrium in solution, and their ratio varies with the nature of the P-OP ligand. Along the series, higher values of the maj/min ratio were observed with complexes bearing less sterically encumbered phosphite groups. In reactions of compounds I with protic reagents removal of one or two ally! ligands has been observed. Thus, reaction of 1h with pentachlorophenol produces the mixed allyl-phenoxide 3h, whereas reaction of la or 1h with tiglic acid produces the corresponding tiglates 4a,h, respectively. In addition, compounds I generate active catalysts for the hydrogenation of tiglic and 2-methyl-2-pentenoic acids. By appropriate optimization of the structure of the P-OP ligand, enantioselectivities up to 89% ee were obtained in these reactions. In addition, complexes I also catalyze the ROMP reaction of norbornene, although low initiation rates have been observed for this process.
• [EN] METHOD FOR THE ENANTIOSELECTIVE SYNTHESIS OF CHIRAL ESTERS, PRODUCT OBTAINED AND USE<br/>[ES] PROCEDIMIENTO DE SÍNTESIS ENANTIOSELECTIVA DE ÉSTERES QUIRALES, PRODUCTO OBTENIDO Y UTILIZACIÓN<br/>[FR] PROCÉDÉ DE SYNTHÈSE ÉNANTIOSÉLECTIVE D'ESTERS CHIRAUX, PRODUIT OBTENU ET UTILISATION
  申请人：CONSEJO SUPERIOR INVESTIGACION

  公开号：WO2014202816A1

  公开（公告）日：2014-12-24

  La presente invención se refiere a un procedimiento para la preparación de diversos ésteres quirales con una elevada pureza enantiomérica, mediante reacciones de hidrogenación catalítica de ésteres de enol. Los ésteres quirales obtenidos y su uso para preparar, mediante hidrólisis, los correspondientes 2- alcanoles quirales son igualmente objetos de la presente invención.