3-(aminomethyl)-N-cyclohexyl-2-fluoro-N-propylbenzamide | 1174410-00-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(aminomethyl)-N-cyclohexyl-2-fluoro-N-propylbenzamide
• CAS: 1174410-00-4
• 化学式: C₁₇H₂₅FN₂O
• 分子量: 292.397
• InChiKey: MIZSZPLRJMSCIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  46.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] SUBSTITUTED AMINO-BENZIMIDAZOLES, MEDICAMENTS COMPRISING SAID COMPOUND, THEIR USE AND THEIR METHOD OF MANUFACTURE<br/>[FR] AMINO-BENZIMIDAZOLES SUBSTITUÉS, MÉDICAMENTS COMPRENANT LEDIT COMPOSÉ, LEUR UTILISATION ET LEUR PROCÉDÉ DE FABRICATION
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2009092566A1

  公开（公告）日：2009-07-30

  The present invention relates to substituted amino-benzimidazoles of general formula (1) wherein the groups R1 to R14 and A, are defined as in the specification and claims and the use thereof for the treatment of Alzheimer's disease (AD) and similar diseases.

  本发明涉及一般式（1）中的取代氨基苯并咪唑，其中基团R1至R14和A如规范和索赔中定义，并其用于治疗阿尔茨海默病（AD）和类似疾病。
• SUBSTITUTED AMINO-BENZIMIDAZOLES, MEDICAMENTS COMPRIMISING SAID COMPOUND, THEIR USE AND THEIR METHOD OF MANUFACTURE
  申请人：Fuchs Klaus

  公开号：US20110288139A1

  公开（公告）日：2011-11-24

  The present invention relates to substituted amino-benzimidazoles of general formula (1) wherein the groups R 1 to R 14 and A, are defined as in the specification and claims and the use thereof for the treatment of Alzheimer's disease (AD) and similar diseases.
• US8426607B2
  申请人：——

  公开号：US8426607B2

  公开（公告）日：2013-04-23