4-(二氟(3,4,5-三氟苯氧基)甲基)-4'-乙基-3,5-二氟-1,1'-联苯 | 303186-19-8

• 物质功能分类: 材料化学 - 配体
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-(二氟(3,4,5-三氟苯氧基)甲基)-4'-乙基-3,5-二氟-1,1'-联苯
• 英文名称: 4-(difluoro(3,4,5-trifluorophenoxy)methyl)-4'-ethyl-3,5-difluoro-1,1'-biphenyl
• 英文别名: 2-[difluoro-(3,4,5-trifluorophenoxy)methyl]-5-(4-ethylphenyl)-1,3-difluorobenzene
• CAS: 303186-19-8
• 化学式: C₂₁H₁₃F₇O
• 分子量: 414.322
• InChiKey: ZTUBOAYBUBUTPH-UHFFFAOYSA-N

物化性质

• 沸点：
  418.3±45.0 °C(Predicted)
• 密度：
  1.358±0.06 g/cm3(Predicted)
• 溶解度：
  溶于甲醇

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  8

安全信息

• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

反应信息

• 作为反应物：
  描述：

  2-唑烷酮 、 4-(二氟(3,4,5-三氟苯氧基)甲基)-4'-乙基-3,5-二氟-1,1'-联苯 在 2,4,5,6-tetrakis(3,6-bis(trifluoromethyl)-9H-carbazol-9-yl)isophthalonitrile 、 C₂₁H₁₅F₁₂NO₄S 作用下， 以 乙腈 为溶剂， 以50 %的产率得到3-(1-(4'-(difluoro(3,4,5-trifluorophenoxy)methyl)-3',5'-difluoro-[1,1'-biphenyl]-4-yl)ethyl)oxazolidin-2-one
  参考文献：
  名称：

  伯和仲苄基 C-H 键亲核胺化的通用光催化策略

  摘要：

  我们报告了一种可见光光氧化还原催化的方法，该方法能够使伯和仲苄基 C(sp 3 )–H 键发生亲核胺化。一种新型酰胺基自由基前体和有机光催化剂串联作用，通过顺序氢原子转移（HAT）和氧化自由基-极性交叉将伯和仲苄基C(sp 3 )–H键转化为碳正离子。生成的碳正离子可以被各种以N为中心的亲核试剂拦截，包括腈（Ritter 反应）、酰胺、氨基甲酸酯、磺酰胺和唑类，以便在统一的反应条件下构建药物相关的 C(sp 3 ) –N键。机理研究表明，HAT 是酰胺自由基介导的，并且光催化剂通过还原猝灭途径发挥作用。这些发现建立了一种温和、无金属和模块化的方案，用于将 C(sp 3 )–H 键快速多样化至胺化产物库。

  DOI：

  10.1021/jacs.3c04912

文献信息

• CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF
  申请人：SHI JIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD.

  公开号：US20150252261A1

  公开（公告）日：2015-09-10

  A cycloheptane derivative as represented by formula (I), and preparation method and use thereof; the compound has photostability and thermostability, wide nematic phase and liquid crystalline state temperature range, and good low-temperature intersolubility, and particularly has low rotary viscosity γ 1 and good dielectric anisotropy (Δ∈>0).

  一种由式（I）表示的环庚烷衍生物，其制备方法和用途；该化合物具有光稳定性和热稳定性，宽的向列相和液晶状态温度范围，良好的低温相容性，特别是具有低旋转粘度γ1和良好的介电各向异性（Δ∈>0）。
• COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME
  申请人：DIC Corporation

  公开号：EP3045512A1

  公开（公告）日：2016-07-20

  A composition exhibits a liquid crystal phase over a wide temperature range, has low viscosity, good low-temperature solubility, and high resistivity and voltage holding ratio, and is stable against heat and light. When this composition is used, IPS or TN-mode liquid crystal display devices that have good display quality and suffer less display failures such as image-sticking and drop marks are produced in high yields. Provided is a composition containing one or more compounds represented by general formula (M-1), one or more compounds represented by general formula (M-3), and one or more compounds represented by general formula (M-4). A liquid crystal display device using the composition is also provided.

  一种组合物在很宽的温度范围内呈现液晶相，具有低粘度、良好的低温溶解性、高电阻率和电压保持比，并且对热和光稳定。使用这种组合物可生产出显示质量好、图像粘连和滴痕等显示故障少的 IPS 或 TN 模式液晶显示设备，产量高。 本发明提供了一种含有通式（M-1）代表的一种或多种化合物、通式（M-3）代表的一种或多种化合物和通式（M-4）代表的一种或多种化合物的组合物。还提供了一种使用该组合物的液晶显示装置。
• NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME
  申请人：DIC Corporation

  公开号：EP3228682A2

  公开（公告）日：2017-10-11

  The present invention relates to a nematic liquid crystal composition which is useful as a material used for liquid crystal display devices and which has a positive dielectric anisotropy (Δε), and the present invention further relates to a liquid crystal display device using such a nematic liquid crystal composition. The liquid crystal composition of the present invention has a liquid crystal phase in a broad temperature range, a low viscosity, good resistance to resolution at low temperature, and high specific resistance and a voltage holding ratio and is stable to heat and light; hence, use of the liquid crystal composition contributes to production of a liquid crystal display device of, for example, an IPS type or a TN type in a good yield, the liquid crystal display device having good display quality and being less likely to suffer from defective display such as screen burn-in and stains of liquid crystal droplets. A liquid crystal display device using the liquid crystal composition of the present invention enables both quick response and a reduction in defective display and is therefore practical; in particular, the liquid crystal composition is useful to active-matrix-driving liquid crystal display devices and can be applied to VA-mode, PSVA-mode, and TN-mode liquid crystal display devices.

  本发明涉及一种向列液晶组合物，它可用作液晶显示装置的材料，并具有正介电各向异性（Δε），本发明还涉及一种使用这种向列液晶组合物的液晶显示装置。 本发明的液晶组合物在较宽的温度范围内具有液晶相，粘度低，在低温下具有良好的抗分解性，以及较高的比电阻和电压保持比，并且对热和光稳定；因此，使用本发明的液晶组合物有助于以较高的产量生产例如 IPS 型或 TN 型的液晶显示设备，该液晶显示设备具有良好的显示质量，并且不易出现诸如屏幕烧毁和液晶液滴污渍等显示缺陷。 使用本发明液晶组合物的液晶显示设备既能实现快速响应，又能减少显示缺陷，因此非常实用；特别是，本发明液晶组合物适用于有源矩阵驱动液晶显示设备，并可应用于 VA 模式、PSVA 模式和 TN 模式液晶显示设备。
• Liquid crystal display device
  申请人：DIC CORPORATION

  公开号：US10011773B2

  公开（公告）日：2018-07-03

  The present invention relates to a liquid crystal display device that includes a particular color filter containing a material containing chiral liquid crystals and a particular dye and/or pigment. The present invention provides a liquid crystal display device that can prevent a decrease in the voltage holding ratio (VHR) of a liquid crystal layer and solve the problem of display defects, such as white spots, variations in alignment, and burn-in. Because liquid crystal display devices according to the present invention characteristically prevent a decrease in the voltage holding ratio (VHR) of a liquid crystal layer and reduces the occurrence of display defects, such as burn-in, the liquid crystal display devices are particularly useful as liquid crystal display devices in IPS mode and FFS mode for active-matrix driving and can be applied to household electrical appliances, automobiles, production facilities, measuring and analytical instruments, and communication devices.

  本发明涉及一种液晶显示装置，其中包括一种特定的彩色滤光片，该滤光片含有手性液晶和特定染料和/或颜料的材料。 本发明提供的液晶显示装置可防止液晶层的电压保持率（VHR）下降，并解决显示缺陷问题，如白斑、排列变化和烧损。 由于根据本发明的液晶显示装置具有防止液晶层的电压保持比（VHR）降低和减少显示缺陷（如烧毁）发生的特点，因此该液晶显示装置特别适用于有源矩阵驱动的 IPS 模式和 FFS 模式的液晶显示装置，并可应用于家用电器、汽车、生产设备、测量和分析仪器以及通信设备。
• Liquid crystal composition and liquid crystal display device
  申请人：JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD.

  公开号：US10457869B2

  公开（公告）日：2019-10-29

  A liquid crystal composition comprises a compound of general formula I serving as a first component; a compound of general formula II-1 and/or general formula II-2 serving as a second component; a compound of general formula III serving as a third component; a compound of general formula IV serving as a fourth component; a compound of general formula V serving as a fifth component; and a compound of general formula VI serving as a sixth component. The liquid crystal composition has at least one characteristic among the characteristics of a large dielectric anisotropy, a large optical anisotropy, a high voltage holding ratio and a low threshold voltage and the like, and is suitable to be used in a liquid crystal display device. Additionally, a liquid crystal display device comprising the liquid crystal composition is also provided.

  一种液晶组合物包括作为第一组分的通式 I 的化合物；作为第二组分的通式 II-1 和/或通式 II-2 的化合物；作为第三组分的通式 III 的化合物；作为第四组分的通式 IV 的化合物；作为第五组分的通式 V 的化合物；以及作为第六组分的通式 VI 的化合物。该液晶组合物具有大介电各向异性、大光学各向异性、高电压保持比和低阈值电压等特性中的至少一种特性，适合用于液晶显示设备。此外，还提供了一种包含该液晶成分的液晶显示设备。