4-((4-chlorophenyl)(hydroxy)methyl)benzaldehyde | 1409975-29-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-((4-chlorophenyl)(hydroxy)methyl)benzaldehyde
• CAS: 1409975-29-6
• 化学式: C₁₄H₁₁ClO₂
• 分子量: 246.693
• InChiKey: ROENBDGLWBMVKM-UHFFFAOYSA-N

物化性质

• 沸点：
  433.6±35.0 °C(Predicted)
• 密度：
  1.293±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

反应信息

• 作为产物：
  描述：

  4-氯苯甲醛 在 碘化铵 、 tetrabutylammonium tetrafluoroborate 、 potassium carbonate 作用下， 以 乙醇 为溶剂， 以83 %的产率得到4-((4-chlorophenyl)(hydroxy)methyl)benzaldehyde
  参考文献：
  名称：

  芳香醛或酮的电化学苯基-羰基偶联反应

  摘要：

  开发了芳香醛或酮的电化学苯基-羰基偶联反应来合成4-(羟基(苯基)甲基)苯甲醛衍生物。该方法表现出高化学选择性、广泛的官能团兼容性、原子经济性和环境友好性，具有良好的潜在适用性。

  DOI：

  10.1021/acs.joc.3c01677

文献信息

• The arylation of aldehydes with arylboronic acids using metal-organic framework Ni(HBTC)BPY as an efficient heterogeneous catalyst
  作者：Nam T.S. Phan、Tung T. Nguyen、Anh H. Ta

  DOI：10.1016/j.molcata.2012.08.015

  日期：2012.12

  A highly crystalline porous Ni(HBTC)BPY was synthesized from the reaction of 1,3,5-benzenetricarboxylic acid, nickel nitrate hexahydrate, and 4,4-bipyridine by a solvothermal method. Physical characterizations of the solid catalyst were achieved by using several techniques, including X-ray powder diffraction (XRD), scanning electron microscope (SEM), transmission electron microscopy (TEM). thermogravimetric analysis (TGA), Fourier transform infrared (FT-IR), atomic absorption spectrophotometry (AAS), and nitrogen physisorption measurements. The Ni(HBTC)BPY exhibited high catalytic activity in the arylation of aldehydes with arylboronic acids to form diarylmethanols. The catalyst could be separated from the reaction mixture by simple filtration or centrifugation, and could be reused without a significant degradation in catalytic activity. No contribution from homogeneous catalysis of active species leaching into the liquid phase was detected. (C) 2012 Elsevier B.V. All rights reserved.