1H-Indole, 6-(4,5-dihydro-1H-imidazol-2-yl)-2-(2-(4-(4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy)phenyl)ethenyl)- | 73819-49-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1H-Indole, 6-(4,5-dihydro-1H-imidazol-2-yl)-2-(2-(4-(4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy)phenyl)ethenyl)-
• 英文别名: 6-(4,5-dihydro-1H-imidazol-2-yl)-2-[(E)-2-[4-[4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy]phenyl]ethenyl]-1H-indole
• CAS: 73819-49-5
• 化学式: C₂₈H₂₅N₅O
• 分子量: 447.5
• InChiKey: KFBKLOLAEPUOEC-UNXLUWIOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  34
• 可旋转键数：
  6
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  73.8
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS
  申请人：United States Government As Represented By The Secretary of The United States Army And The U.S. Army Medical Research & Materiel Command

  公开号：EP1945209B1

  公开（公告）日：2018-05-30
• Small Molecule Inhibitors of Botulinum Neurotoxins
  申请人：Bavari Sina

  公开号：US20070112049A1

  公开（公告）日：2007-05-17

  Disclosed herein are methods of inhibiting the activity of Botulinum neurotoxin A metalloprotease with the compounds disclosed herein. Also disclosed are methods of treating, inhibiting or preventing intoxication caused by bacteria of at least one bacterial strain in a subject, and pharmaceutical and cosmetic compositions comprising the compounds disclosed herein.
• US7825154B2
  申请人：——

  公开号：US7825154B2

  公开（公告）日：2010-11-02