(S)-phenyl[(2S)-4-(phenylmethyl)morpholin-2-yl]methyl-2-propylphenyl sulfide | 668470-99-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (S)-phenyl[(2S)-4-(phenylmethyl)morpholin-2-yl]methyl-2-propylphenyl sulfide
• 英文别名: (2S)-4-benzyl-2-[(S)-phenyl-(2-propylphenyl)sulfanylmethyl]morpholine
• CAS: 668470-99-3
• 化学式: C₂₇H₃₁NOS
• 分子量: 417.615
• InChiKey: CUFVSKGDWAAYHE-BDYUSTAISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  30
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  37.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• 2-(PHENYLTHIOMETHYL)- MORPHOLINE DERIVATIVES FOR USE AS SELECTIVE NOREPINEPHRINE REUPTAKE INHIBITORS
  申请人：ELI LILLY AND COMPANY

  公开号：EP1534291B1

  公开（公告）日：2008-11-12
• Treatment of hot flashes, impulse control disorders and personality change due to a general medical condition
  申请人：Allen John Albert

  公开号：US20070015786A1

  公开（公告）日：2007-01-18

  Selective norepinephrine reuptake inhibitors are useful for the prevention or treatment of hot flashes, vasomotor symptoms, impulse control disorders or personality change due to a general medical condition.
• Treatment of stuttering and other communication disorders with norepinephrine reuptake inhibitors
  申请人：Kelsey Kenneth Douglas

  公开号：US20070032554A1

  公开（公告）日：2007-02-08

  Provided are methods and medicaments for treating stuttering or another communication disorder, comprising administering to a patient in need of such treatment an effective amount of a selective norepinephrine reuptake inhibitor.
• Treatment of learning disabilities and motor skills disorder with norepinephrine reuptake inhibitors
  申请人：Sumner Russell Calvin

  公开号：US20070105960A1

  公开（公告）日：2007-05-10

  Provided are methods and medicaments for treating a learning disability or a Motor Skills Disorder, comprising administering to a patient in need of such treatment an effective amount of a selective norepinephrine reuptake inhibitor.
• US7384941B2
  申请人：——

  公开号：US7384941B2

  公开（公告）日：2008-06-10