Pyridoxal oxoglurate | 40273-30-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Pyridoxal oxoglurate
• 英文别名: 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde;2-oxopentanedioic acid
• CAS: 40273-30-1
• 化学式: C13H15NO8
• 分子量: 313.26
• InChiKey: MUXYIGOUJRUBPG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.09
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  162
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• Compositions of matter containing L-glutamine and pyridoxal-alpha-ketoglutarate
  申请人：——

  公开号：US20020188010A1

  公开（公告）日：2002-12-12

  Compositions having synergistic effects which make it possible to obtain full beneficial effects of L-glutamine while avoiding the toxic effects that may accompany administration of L-glutamine. This benefit is attained by administration of L-glutamine in conjunction with pyridoxal-alpha-ketoglutarate (PAK). Compositions containing PAK:L-glutamine at a ratio (w/w) of from 1:1 to 1:10 are effective for providing beneficial effects of L-glutamine at nontoxic levels.

  具有协同增效作用的复合物，既能获得 L-谷氨酰胺的全部益处，又能避免服用 L-谷氨酰胺可能产生的毒副作用。通过将 L-谷氨酰胺与吡哆醛-α-酮戊二酸（PAK）一起服用，可获得这种益处。PAK与L-谷氨酰胺的比例（重量/重量）为1:1至1:10的组合物能有效地在无毒的水平上提供L-谷氨酰胺的益处。
• Methods for the treatment of HIV-1 related fat maldistribution, fasting hyperlipidemia and modification of adipocyte physiology
  申请人：Pacioretty M. Linda

  公开号：US20080114065A1

  公开（公告）日：2008-05-15

  Methods for treating or preventing metabolic dysregulation of adipocytes resulting from HIV-1 infection or chronic inflammation are disclosed. The compositions contain a conjugated fatty acid, a thiol-containing compound and a bioavailable form of trivalent chromium.
• NUTRITIONAL SUPPLEMENTS FOR HEALTHY MEMORY AND MENTAL FUNCTION
  申请人：Smith Kyl L.

  公开号：US20080213401A1

  公开（公告）日：2008-09-04

  The invention relates to compositions for supporting healthy memory and optimizing mental energy and methods for improving, preventing, and treating mental disorders or deterioration. The compositions of the invention can be formulated as nutritional or dietary supplements.
• US6545044B2
  申请人：——

  公开号：US6545044B2

  公开（公告）日：2003-04-08
• US7972633B2
  申请人：——

  公开号：US7972633B2

  公开（公告）日：2011-07-05