1-(4,4-difluorobutyl)naphthalene | 1228151-04-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-(4,4-difluorobutyl)naphthalene
• CAS: 1228151-04-9
• 化学式: C₁₄H₁₄F₂
• 分子量: 220.262
• InChiKey: CIKFQQQXGYCEFK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-烯丙基萘 、 二氟乙酸酐 在 N-羟基邻苯二甲酰亚胺 、 tris(2,2'-bipyridyl)ruthenium dichloride 作用下， 以 1,2-二氯乙烷 为溶剂， 以77 %的产率得到1-(4,4-difluorobutyl)naphthalene
  参考文献：
  名称：

  可见光诱导未活化烯烃与二氟乙酸酐的氢二氟甲基化

  摘要：

  我们在此描述了一种实用且有效的方案，通过结合光催化和N-羟基邻苯二甲酰亚胺活化，使用容易获得的二氟乙酸酐作为二氟甲基源，对未活化的烯烃进行氢二氟甲基化。该方法具有底物范围广、与各种官能团具有良好的相容性的特点，已有50多个例子证明，包括生物活性分子和药物衍生物。机理研究表明N-羟基邻苯二甲酰亚胺也可能作为氢原子供体。

  DOI：

  10.1021/acs.joc.4c00702

文献信息

• Synthesis and hydrogenation of (E)-γ-aryl-γ-morpholino-α-trifluoromethylated allyl alcohols through the reaction of trifluoroacetaldehyde ethyl hemiacetal with enamines
  作者：Kazumasa Funabiki、Yoshihiro Murase、Yudai Furuno、Yasuhiro Kubota、Masahiro Ebihara、Masaki Matsui

  DOI：10.1016/j.tet.2010.03.019

  日期：2010.5

  Treatment of trifluoroacetaldehyde ethyl hemiacetal with enamines, derived from acetophenone derivatives, at room temperature gave (E)-1,1,1-trifluoro-4-morpholino-4-aryl-but-3-en-2-ols, which are intermediates for preparation of the β-trifluoromethylated aldol products, 4,4,4-trifluoro-3-hydroxy-1-aryl-butan-1-ones. The structure of the intermediate (E)-1,1,1-trifluoro-4-morpholino-4-(4-nitrophenyl)-but-3-en-2-ols

  在室温下，用苯乙酮衍生物衍生的烯胺处理三氟乙醛乙基半缩醛，得到中间体的（E）-1,1,1,1-三氟-4-吗啉代-4-芳基-丁-3-烯-2-醇用于制备β-三氟甲基化的羟醛产物，4,4,4-三氟-3-羟基-1-芳基-丁丹-1-酮。中间体（E）-1,1,1-三氟-4-吗啉代-4-（4-硝基苯基）-丁-3-烯-2-醇的结构可以通过1 H，13 C NMR，IR鉴定和X射线晶体学。此外，中间体（E）-1,1,1,1-三氟-4-吗啉代-4-芳基-丁-3-烯-2-醇与氢在催化量（10 mol％）的钯/碳在三氟乙醇中的存在下于110℃平稳进行在室温下以良好至优异的产率得到1,1,1-三氟-4-芳基-2-丁醇。
• METHOD FOR CONTROLLING ARTHROPOD PEST
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20150344466A1

  公开（公告）日：2015-12-03

  An amide compound represented by formula (I): [wherein A represents a 3- to 7-membered saturated heterocyclic ring which contains, as ring-forming component(s), one or more atoms or groups selected from the group consisting of an oxygen atom and —S(O) t —, t represents 0, etc., R 1 and R 2 are the same or different and represent a hydrogen atom, etc., n represents 0, etc., the following formula (II): represents a 5-membered aromatic ring, in which Z represents a nitrogen atom or a carbon atom and X 1 , X 2 and X 3 are the same or different and represent a nitrogen atom, etc., R 3 and R 4 are the same or different and represent a hydrogen atom, etc., m represents 0 to 2, Q represents one group selected from group A or a C1 to C8 chain hydrocarbon group optionally having one group selected from group A, Y represents an oxygen atom, etc., u represents 0, etc., and v represents 0, etc.] has excellent arthropod pest controlling effects.

  化合物式(I)所代表的酰胺化合物：[其中A代表一个3到7个成员的饱和杂环环，该环包含作为环构成组分之一或多个原子或基团，所选自氧原子和—S（O）t—群，t代表0等；R1和R2相同或不同，代表氢原子等；n代表0等；下列式子(II)代表一个5个成员的芳香环，在该环中Z代表一个氮原子或一个碳原子，X1、X2和X3相同或不同，代表氮原子等，R3和R4相同或不同，代表氢原子等，m代表0到2，Q代表从群A中选择的一个群或一个C1到C8链烃基团，该基团可以选择从群A中选择的一个群，Y代表氧原子等，u代表0等，v代表0等]具有优良的节肢动物害虫控制效果。
• POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION
  申请人：Asahi Kasei Chemicals Corporation

  公开号：EP2915803A1

  公开（公告）日：2015-09-09

  The present invention relates to a polyisocyanate composition comprising, on the basis of the total mass of the polyisocyanate composition, 97 weight % or more of a polyisocyanate, and 2.0 mass ppm or more and 1.0×104 mass ppm or less of a compound having at least one unsaturated bond in which the compound is a different compound from the polyisocyanate, or 5.0 mass ppm or more and 2.0×104 mass ppm or less of at least one inactive compound selected from the group consisting of a hydrocarbon compound, an ether compound, a sulfide compound, a halogenated hydrocarbon compound, a Si-containing hydrocarbon compound, a Si-containing ether compound, and a Si-containing sulfide compound.

  本发明涉及一种多异氰酸酯组合物，以该多异氰酸酯组合物的总质量为基准，该组合物包含 97 重量％或以上的多异氰酸酯，以及 2.0 质量 ppm 或以上且 1.0×104 质量 ppm 或以下的至少具有一个不饱和键的化合物，其中该化合物是与多异氰酸酯不同的化合物，或 5.0 质量 ppm 或以上且 2.0×104 质量 ppm 或以下的至少一种非活性化合物，该化合物选 自烃化合物、醚化合物、硫化物化合物、卤代烃化合物、含硅烃化合物、含硅醚化合物和含硅硫 化物组成的组。
• ISOCYANATE COMPOSITION, ISOCYANATE POLYMER PRODUCTION METHOD, AND ISOCYANATE POLYMER
  申请人：ASAHI KASEI KABUSHIKI KAISHA

  公开号：EP3527603A1

  公开（公告）日：2019-08-21

  The present invention provides an isocyanate composition including an isocyanate compound having an ethylenically unsaturated bond, a compound represented by formula (1) (in the formula, R1 represents an a-valent organic group, R2 represents a monovalent organic group, a represents an integer of 1 or 2), and/or a compound having a UV absorption in a spectral region of a decamer or higher isocyanate measured by gel permeation chromatography; and an isocyanate composition including an isocyanate compound having an ethylenically unsaturated bond, or a compound having at least one unsaturated bond other than an unsaturated bond constituting an aromatic ring or an inert compound such as a hydrocarbon compound or the like and having a carbon-carbon unsaturated bond other than an unsaturated bond constituting an aromatic ring; or the like.         R1-(COO-R2)a     (1)

  本发明提供了一种异氰酸酯组合物，包括具有乙烯不饱和键的异氰酸酯化合物、由式(1)代表的化合物（式中，R1代表一价有机基团，R2代表一价有机基团，a代表1或2的整数），和/或通过凝胶渗透色谱法测量在十聚体或更高异氰酸酯光谱区具有紫外吸收的化合物；异氰酸酯组合物，包括具有乙烯不饱和键的异氰酸酯化合物，或具有至少一个不饱和键（构成芳香环的不饱和键除外）的化合物，或惰性化合物（如烃类化合物等），且具有碳-碳不饱和键（构成芳香环的不饱和键除外）的化合物；或类似物。 R1-(COO-R2)a (1)
• ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER
  申请人：ASAHI KASEI KABUSHIKI KAISHA

  公开号：EP3527600A1

  公开（公告）日：2019-08-21

  An isocyanate composition according to the present invention contains: a difunctional or more-functional isocyanate compound; and 1.0 ppm by mass to 1.0 × 104 ppm by mass, based on the isocyanate compound, of a compound having at least one unsaturated bond excluding unsaturated bonds constituting an aromatic ring, the compound being different from the isocyanate.

  根据本发明的异氰酸酯组合物含有：双官能团或更多官能团的异氰酸酯化合物；以及以异氰酸酯化合物为基准，质量分数为 1.0 ppm 至 1.0 × 104 ppm 的化合物，该化合物具有至少一个不饱和键，不包括构成芳香环的不饱和键，该化合物不同于异氰酸酯。