2--5-methyl-pyrrolidin | 90872-76-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2--5-methyl-pyrrolidin
• 英文别名: 5'-Methyl-nornicotin, 2--5-methyl-pyrrolidin；5'-Methyl-nornicotin；3-(5-methyl-pyrrolidin-2-yl)-pyridine；3-(5-Methylpyrrolidin-2-yl)pyridine
• CAS: 90872-76-7
• 化学式: C₁₀H₁₄N₂
• 分子量: 162.235
• InChiKey: DDETYHCMRKGPKO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  24.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] THERAPEUTIC COTININE COMPOSITIONS<br/>[FR] COMPOSITIONS THÉRAPEUTIQUES À BASE DE COTININE
  申请人：UNIV LOUISVILLE RES FOUND

  公开号：WO2008103818A1

  公开（公告）日：2008-08-28

  [EN] The present invention provides methods and compositions for treating acute and/or chronic inflammation with cotinine or a pharmaceutically acceptable salt thereof.
  [FR] La présente invention a pour objet des procédés et des compositions destinés au traitement d'une inflammation aiguë et/ou chronique avec de la cotinine ou l'un de ses sels acceptables sur le plan pharmaceutique.
• [EN] SYSTEM AND PROCESS FOR TOBACCOLESS NICOTINE DELIVERY<br/>[FR] SYSTÈME ET PROCÉDÉ D'ADMINISTRATION DE NICOTINE SANS TABAC
  申请人：UMAGINATION LABS LP

  公开号：WO2009073690A1

  公开（公告）日：2009-06-11

  A tobaccoless nicotine delivery device permits delivery of nicotine in a manner similar to a cigarette. The device may include an impermeable outer layer surrounding a micro-encapsulated nicotine layer that includes a measured amount of nicotine in a form that allows nicotine vapor to be released upon rupture of the micro¬ encapsulation. A permeable membrane may be disposed adjacent to the micro¬ encapsulated nicotine layer that allows pressure to be applied to the micro-encapsulated nicotine layer while permitting permeation of released nicotine into a central channel for inhalation by a user. A mouthpiece may be disposed at an open end of the central channel in order to provide air resistance to simulate the inhalation effect of a cigarette.