5-hexen-1-yl 2-(4-t-butylphenyl)-5-hydroxymethyl-7-methoxy-benzo[b]furan-3-carboxylate | 500117-59-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 2-芳基苯并呋喃类黄酮
• 英文名称: 5-hexen-1-yl 2-(4-t-butylphenyl)-5-hydroxymethyl-7-methoxy-benzo[b]furan-3-carboxylate
• 英文别名: Hex-5-enyl 2-(4-tert-butylphenyl)-5-(hydroxymethyl)-7-methoxy-1-benzofuran-3-carboxylate
• CAS: 500117-59-9
• 化学式: C₂₇H₃₂O₅
• 分子量: 436.548
• InChiKey: INDYOVMRRUGHMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  32
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  68.9
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Benzo[b]furan dimers
  申请人：——

  公开号：US20040110949A1

  公开（公告）日：2004-06-10

  Benzo[b]furan dimers and processes for their preparation are provided. The invention provides a synthetic process for the preparation of benzo[b]furan dimer using mild reaction conditions, which provides a high substituent tolerance and is appropriate for use in solid phase syntheses for producing a library of benzo[b]furan dimers for biological screening.

  本发明提供了苯并[b]呋喃二聚体及其制备方法。该发明提供了一种合成苯并[b]呋喃二聚体的方法，使用温和的反应条件，具有高代用基耐受性，并适用于固相合成，以制备苯并[b]呋喃二聚体的文库，用于生物筛选。
• US6855822B2
  申请人：——

  公开号：US6855822B2

  公开（公告）日：2005-02-15
• [EN] BENZO(b)FURAN DIMERS<br/>[FR] DIMERES DE BENZO(B)FURANE
  申请人：VIVOQUEST INC

  公开号：WO2004000764A2

  公开（公告）日：2003-12-31

  Benzo[b]furan dimers and processes for their preparation are provided. The invention provides a synthetic process for the preparation of benzo[b]furan dimer using mild reaction conditions, which provides a high substituent tolerance and is appropriate for use in solid phase syntheses for producing a library of benzo[b]furan dimers for biological screening.