α-Diphenylamino-keton | 41110-04-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: α-Diphenylamino-keton
• 英文别名: 1-(N-phenylanilino)propan-2-one
• CAS: 41110-04-7
• 化学式: C₁₅H₁₅NO
• 分子量: 225.29
• InChiKey: MFNKZWKBCXLLEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  α-Diphenylamino-keton 在 Hoveyda-Grubbs catalyst second generation 作用下， 以 四氢呋喃 为溶剂， 反应 18.5h， 生成
  参考文献：
  名称：

  3-氨基色烷和四氢喹啉作为选择性5-HT2B，5-HT7或σ1受体配体。

  摘要：

  苯乙胺主链是在多种G蛋白偶联受体（GPCR）配体中发现的优先亚结构。这包括内源性神经递质和活性药物。广泛评估了20多种结构独特的杂环苯乙胺衍生物的GPCR亲和力。确定了5-HT2B，5-HT7和σ1受体的选择性配体，每个受体的纳摩尔摩尔亲和力均较低。σ1受体亲和力在细胞试验中得到支持，该试验为氧化应激下细胞存活的增加提供了证据。

  DOI：

  10.1021/acsmedchemlett.9b00225

文献信息

• Process for preparing acyloxybenzenesulfonates
  申请人：Clariant GmbH

  公开号：US20040198995A1

  公开（公告）日：2004-10-07

  A process for preparing acyloxybenzenesulfonates by reacting a carboxylic acid derivative with a salt of a phenolsulfonic acid in the presence of an antioxidant, preferably 2,6-di-tert-butyl-4-methylphenol. The addition of such antioxidants gives a product having a high color quality.

  通过在抗氧化剂存在下，将羧酸衍生物与苯磺酸盐反应，制备乙酰氧基苯磺酸酯的方法，最好使用2,6-二叔丁基-4-甲基苯酚。添加这种抗氧化剂可使产品具有高色彩质量。
• NON-XENOESTROGENIC STABILIZERS FOR ORGANIC MATERIALS
  申请人：——

  公开号：US20010053805A1

  公开（公告）日：2001-12-20

  A non-xenoestrogenic phosphorus-containing stabilizer for organic materials is disclosed wherein the stabilizer is selected from the group consisting of phosphorus-containing compounds of the structures 1 wherein y in an integer of from 6 to 20 , and 2 where Z is a linking group, m is 0 or 1 , n is an integer of at least 2 , the asterisks are independently selected terminal groups, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are independently selected from the group consisting of hydrogen, alkyl groups, aralkyl groups, or halogen groups and Q is selected from the group consisting of 3 where R 11 is alkyl or aralkyl, and 4

  披露了一种非异雌激素磷含稳定剂，其中所述稳定剂选自由结构1的含磷化合物组成的群体，其中y为6到20的整数；以及结构2中，Z为连接基团，m为0或1，n为至少2的整数，星号独立选择末端基团，R1、R2、R3、R4、R5、R6、R7和R8独立选择自氢、烷基、芳基烷基或卤素基团组成的群体，Q选自由结构3中R11为烷基或芳基烷基的群体，以及结构4中的群体。
• Non-xenoestrogenic stabilizers for organic materials
  申请人：Archibald R. Scott

  公开号：US20050080172A1

  公开（公告）日：2005-04-14

  A non-xenoestrogenic phosphorus-containing stabilizer for organic materials is disclosed wherein the stabilizer is selected from the group consisting of phosphorus-containing compounds of the structures wherein y in an integer of from 6 to 20, and where Z is a linking group, m is 0 or 1, n is an integer of at least 2, the asterisks are independently selected terminal groups, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are independently selected from the group consisting of hydrogen, alkyl groups, aralkyl groups, or halogen groups and Q is selected from the group consisting of where R 11 , is alkyl or aralkyl, and

  本文披露了一种非黄体酮类磷含有稳定剂，用于有机材料中，其中所述稳定剂选自以下化合物组中的磷含有化合物结构：其中y为6至20的整数，Z为连接基团，m为0或1，n为至少2的整数，星号表示独立选择的末端基团，R1、R2、R3、R4、R5、R6、R7和R8独立选择自氢、烷基、芳基烷基或卤素基团组成的组，Q选自以下组中的一种：其中R11为烷基或芳基烷基。
• METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME
  申请人：Tanaka Ken

  公开号：US20110146877A1

  公开（公告）日：2011-06-23

  The invention provides a method for producing a modified conjugated diene (co)polymer, the method including comprising: a modification reaction step including causing an organic silane compound to react with a conjugated diene (co)polymer having an active site at the active site, the organic silane compound having a characteristic group for forming a silanol group through hydrolysis and, in the vicinity of the characteristic group, (i) a functional group which binds the organic silane compound to the conjugated diene (co)polymer via addition to or substitution at the active site and which promotes reaction between the silanol group and a reinforcing filler after the addition or substitution reaction, or (ii) a functional group which promotes reaction between the silanol group and a reinforcing filler, and a hydrolyzation step performed after the modification reaction step; a modified conjugated diene (co)polymer having, at a molecular end of the conjugated diene (co)polymer, a silanol group, and a functional group in the vicinity of the silanol group, the functional group accelerating reaction between the silanol group and the reinforcing filler; a rubber composition containing the (co)polymer and carbon black having specific characteristics; and a tire formed from the rubber composition.

  本发明提供了一种生产改性共轭二烯（共）聚合物的方法，该方法包括：修改反应步骤，包括使有机硅化合物与具有活性位点的共轭二烯（共）聚合物在活性位点处反应，所述有机硅化合物具有通过水解形成硅醇基团的特征基团，在特征基团附近，（i）通过加成或置换作用于活性位点，将有机硅化合物与共轭二烯（共）聚合物结合的功能基团，并促进加成或置换反应后硅醇基团和增强填料之间的反应，或（ii）促进硅醇基团和增强填料之间反应的功能基团；修改反应步骤后进行水解步骤；在共轭二烯（共）聚合物的分子末端具有硅醇基团和硅醇基团附近的功能基团的改性共轭二烯（共）聚合物；包含具有特定特性的碳黑的橡胶组合物；以及由该橡胶组合物形成的轮胎。
• Photo-deterioration inhibitor and composition containing the same
  申请人：DAIKYO GOMU SEIKO LTD.

  公开号：EP0527274A1

  公开（公告）日：1993-02-17

  A photo-deterioration inhibitor containing a compound represented by the general formula (I): where R₁ and R₂ may be same or different and represent hydrogen, chlorine, hydroxyl group, alkoxy group having 1-18 carbon atoms, aryloxy group having 6-8 carbon atoms and mono- or dialkylamino group having 1-4 carbon atoms, respectively, and R₃ and R₄ may be same or different and represent hydrogen, chlorine, alkyl group having 1-8 carbon atoms, methoxy group and ethoxy group; a photo-deterioration inhibitory resin composition containing a polyolefin resin or polyolefin resin composition and the compound represented by the general formula (I); and a container formed from the photo-deterioration inhibitory resin composition containing the polyolefin resin or polyolefin resin composition and the compound represented by the general formula (I).

  一种含有通式(I)所代表的化合物的光降解抑制剂，其中R₁和R₂可以相同或不同，分别代表氢、氯、羟基、具有1-18个碳原子的烷氧基、具有6-8个碳原子的芳氧基和1-4个碳原子的单烷基或双烷基氨基，而R₃和R₄可以相同或不同，分别代表氢、氯、具有1-8个碳原子的烷基、甲氧基和乙氧基；一种含有聚烯烃树脂或聚烯烃树脂组成的光降解抑制树脂组合物和通式(I)所代表的化合物的光降解抑制树脂组合物；以及由含有聚烯烃树脂或聚烯烃树脂组成和通式(I)所代表的化合物的光降解抑制树脂组合物形成的容器。