5-bromo-4-ethynyl-1-methyl-1H-pyrazole | 2158223-29-9

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 芳基卤化物
• 英文名称: 5-bromo-4-ethynyl-1-methyl-1H-pyrazole
• 英文别名: 5-bromo-4-ethynyl-1-methylpyrazole
• CAS: 2158223-29-9
• 化学式: C₆H₅BrN₂
• 分子量: 185.023
• InChiKey: MLGWHWAHELALCG-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  1-Boc-pyrazole-4-boronic acid pinacol ester 、 5-bromo-4-ethynyl-1-methyl-1H-pyrazole 在 四(三苯基膦)钯 作用下， 生成 4-ethynyl-2-methyl-1'H,2H-3,4'-bipyrazole
  参考文献：
  名称：

  PYRIDINE N-OXIDE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

  摘要：

  The present invention is directed to pyridine N-oxide derivatives, stereoisomers, isotopologues, isotopomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.

  公开号：

  US20230091768A1