(4-Chloro-phenyl)-(4'-hydroxy-biphenyl-4-yl)-methanone | 38304-24-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-Chloro-phenyl)-(4'-hydroxy-biphenyl-4-yl)-methanone
• 英文别名: (4-Chlorophenyl)(4'-hydroxy[1,1'-biphenyl]-4-yl)methanone；(4-chlorophenyl)-[4-(4-hydroxyphenyl)phenyl]methanone
• CAS: 38304-24-4
• 化学式: C₁₉H₁₃ClO₂
• 分子量: 308.764
• InChiKey: WMSCJRUWJYDUBN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Production of arylophenones
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0075390A1

  公开（公告）日：1983-03-30

  Production of an arylophenone by reacting an aromatic carboxylic acid of formula Ar(-CO2H)n, where n is preferably 1 or 2, with an aromatic compound of formula Ar'-H to produce an arylophenone of formula Ar(-CO-Ar')n, wherein the process is carried out in the presence of a fluoroalkane sulphonic acid, preferably trifluoromethane sulphonic acid. For example, 4,4'-dihydroxy-benzophenone is prepared from 4-hydroxy- benzoic acid and phenol.

  通过式 Ar(-CO2H)n（其中 n 最好为 1 或 2）的芳香族羧酸与式 Ar'-H 的芳香族化合物反应生成式 Ar(-CO-Ar')n的芳基苯酮，其中该过程是在氟烷磺酸（最好是三氟甲烷磺酸）存在下进行的。例如，4,4'-二羟基二苯甲酮由 4-羟基苯甲酸和苯酚制备。
• Process for the Preparation of Polyetherketones
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0182648A2

  公开（公告）日：1986-05-28

  Polyaryletherketones are prepared by polymerisation of a halogen-containing aryl ketone in the presence of a stoichiometric excess of a base and a copper salt. The halogen-containing aryl ketone may be 4-chloro-4'-hydroxybenzophenone. A basic copper salt may be used but the base used to provide the excess of base is an alkali metal hydroxide, carbonate or bicarbonate.

  多芳基醚酮是通过含卤芳基酮在过量的碱和铜盐的存在下发生聚合反应而制备的。 含卤芳基酮可以是 4-氯-4'-羟基二苯甲酮。 可以使用碱式铜盐，但提供过量碱的碱是碱金属氢氧化物、碳酸盐或碳酸氢盐。
• Aromatic polymer and process for its preparation
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0222536A2

  公开（公告）日：1987-05-20

  Aromatic polyethers are produced by polycondensing monomers containing phenolic groups and aromatic halogen, at least some of the aromatic halogen - containing monomers being free of activating groups such as -CO- or -SO2-, in the presence of a copper-containing catalyst and of a basic alkali metal compound present in stoichiometric excess relative to phenolic groups and copper. The products include new polyethers, particularly containing the repeating unit Ph1-PH1-O alone or with ketone containing or sulphone-containing units, where Ph' is phenylene.

  芳香族聚醚是在含铜催化剂和碱金属化合物（相对于酚类基团和铜）存在下，通过缩聚含有酚类基团和芳香卤素的单体（至少其中一些含芳香卤素的单体不含-CO-或-SO2-等活化基团）而制得的。产品包括新的聚醚，特别是单独含有重复单元 Ph1-PH1-O 或含有酮或含砜单元的聚醚，其中 Ph' 为亚苯基。
• Aromatic Polymer
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0232019A2

  公开（公告）日：1987-08-12

  A polymer contains repeating units and (Where Ph is para-phenylene) linked together by ether linkages, and has a relatively higher molecular weight corresponding to an inherent viscosity of at least 0.4. Preferred polymers contain 65-85 mole % of units I relative to the total of and II and are characterised by inter alia high solvent resistance, glass transition temperature over 200°C and melting temperature below 400°C. Processes for making the polymers and composite containing them are also provided.

  聚合物含有通过醚键连接在一起的重复单元 I 和 II（其中 Ph 为对位亚苯基），分子量相对较高，固有粘度至少为 0.4。
• Process for production of aromatic polyethers
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP0306051A1

  公开（公告）日：1989-03-08

  An improved process for producing aromatic polyethers by condensation polymerizing aromatic dihydroxy compounds represented by the general formula: HO-Ar-OH and aromatic dichloro compounds represented by the general formula: Cl-Ar¹-Y-Ar²-Cl, or condensation polymerizing monohydroxymonochloro aromatic compounds represented by the general formula: HO-Ar¹-Y-Ar²-Cl in the above formulae, Ar, Ar¹, Ar² are as defined in the specification) in the presence of alkali metal compounds comprising a combination of alkali metal carbonates comprising carbonate and/or hydrogencarbonate of an alkali metal, e.g., potassium, and alkali metal fluorides. In accordance with the present process, high molecular weight aromatic polyethers can be efficiently produced from aromatic chloro compounds which are inexpensive and easily available.

  一种通过通式为：HO-Ar-OH 的芳香族二羟基化合物和通式为：HO-Ar-OH 的芳香族二氯化合物的缩合聚合生产芳香族聚醚的改进工艺：HO-Ar-OH和通式为Cl-Ar¹-Y-Ar²-Cl的芳香族二氯化合物缩合聚合生产芳香族聚醚的改进工艺：Cl-Ar¹-Y-Ar²-Cl，或通过缩合聚合通式为HO-Ar¹-Y-Ar²-Cl，在上式中，Ar、Ar¹、Ar²如说明书中所定义）的碱金属化合物的存在下，该碱金属化合物由碱金属碳酸盐（包括碱金属的碳酸盐和/或碳酸氢盐，如钾）和碱金属氟化物组合而成。 根据本发明的工艺，可以从芳香族氯化合物中有效地生产出高分子量的芳香族聚醚，而芳香族氯化合物价格低廉，容易获得。