(E)-2-methyl-1-methylsulfanyl-but-2-ene | 137175-32-7

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: (E)-2-methyl-1-methylsulfanyl-but-2-ene
• 英文别名: (E)-2-methyl-1-(methylthio)-2-butene；trans-1-Methylmercapto-2-methyl-buten-(2)；2-Methyl-1-methylthio-2-butene；(E)-2-methyl-1-methylsulfanylbut-2-ene
• CAS: 137175-32-7
• 化学式: C₆H₁₂S
• 分子量: 116.227
• InChiKey: PBWZEERIWACABP-GQCTYLIASA-N

物化性质

• 沸点：
  143.5±9.0 °C(Predicted)
• 密度：
  0.861±0.06 g/cm3(Predicted)
• 物理描述：
  Clear, colourless liquid; Cooked brown and roasted meat aroma
• 溶解度：
  Very slightly soluble in water; soluble in non-polar solvents
• 折光率：
  1.468-1.474

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  7
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  甲硫醇 、 天然橡胶 生成 (E)-2-methyl-1-methylsulfanyl-but-2-ene
  参考文献：
  名称：

  Organic Sulfur Compounds. VIII. Addition of Thiols to Conjugated Diolefins

  摘要：

  DOI：

  10.1021/ja00879a020

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• ORGANIC SULFUR COMPOUND AND ITS USE FOR CONTROLLING HARMFUL ARTHROPOD
  申请人：Miyazaki Hiroyuki

  公开号：US20100160434A1

  公开（公告）日：2010-06-24

  There is provided an organic sulfur compound having an excellent controlling effect on harmful arthropods represented by the formula (I): wherein, R 1 represents a C3-C10 alkenyl group optionally substituted with at least one halogen atom, a C3-C10 alkynyl group optionally substituted with at least one halogen atom, or the like, R 2 represents a cyano group or the like, R 3 represents a hydrogen atom, a halogen atom or a C1-C4 alkyl group, R 4 represents a C1-C5 fluoroalkyl group, and n represents 0, 1 or 2.

  提供了一种有机硫化合物，其对由式（I）所代表的有害节肢动物具有优异的控制效果：其中，R1代表C3-C10烯基，可选地取代至少一个卤素原子，C3-C10炔基，可选地取代至少一个卤素原子或类似基团；R2代表氰基或类似基团；R3代表氢原子、卤素原子或C1-C4烷基；R4代表C1-C5氟烷基；n代表0、1或2。
• Flavouring a foodstuff with compounds containing a sulphur atom linked to two specific atoms or groups
  申请人：QUEST INTERNATIONAL B.V.

  公开号：EP1142490A1

  公开（公告）日：2001-10-10

  The invention relates to a process for flavouring foodstuffs by incorporating therein an effective amount of at least one compound R1-S-R2 with a specific, well defined structure such as (E)-2-methyl-1-(methylthio)-2-butene; S-ethyl thioformate; S-ethyl-2-(acetylamino)thioacetate; N-(2-methylthioethyl)acetamide; methyl-2-mercaptopropionate; propyl-2-mercaptopropionate; 2-(isopropylthio)pentane; 2-propenylthiol; 4-methyl-2-3H-thiazolone or tautomer; and 2,3-dimethyl-4-formylthiophene. The invention also covers a foodstuff and/or a flavouring concentrate containing at least one of the above identified compounds.

  本发明涉及一种食品调味工艺，在食品中加入有效量的至少一种具有特定的、明确的结构的化合物R1-S-R2，如(E)-2-甲基-1-(甲硫基)-2-丁烯；硫代甲酸 S-乙基酯；N-(2-甲硫基乙基)乙酰胺；2-巯基丙酸甲酯；2-巯基丙酸丙酯；S-乙基-2-(乙酰氨基)硫代乙酸酯；N-(2-甲硫基乙基)乙酰胺；2-巯基丙酸甲酯；2-巯基丙酸丙酯；2-(异丙硫基)戊烷；2-丙烯基硫醇；4-甲基-2-3H-噻唑酮或同系物；以及 2,3-二甲基-4-甲酰基噻吩。本发明还包括含有至少一种上述化合物的食品和/或浓缩香精。
• 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES
  申请人：Sankyo Company, Limited

  公开号：EP1304325A1

  公开（公告）日：2003-04-23

  Provided is a 5-(m-cyanobenzylamino)pyrazole derivative represented by the following formula:    wherein: R1 represents a C1-6 alkyl group, a C3-7 cycloalkyl group or a phenyl group; R2 represents a hydrogen atom or a C1-6 alkyl group; R3 represents a C1-6 alkyl, etc., R4 represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, etc., Y represents a C1-6 alkyl group, etc.; and n is an integer of 0 to 4; or a salt thereof.

  本发明提供了由下式表示的 5-(间氰基苄基氨基)吡唑衍生物： 其中 R1代表C1-6烷基、C3-7环烷基或苯基； R2代表氢原子或C1-6烷基 R3 代表 C1-6 烷基等、 R4 代表氢原子、卤素原子、C1-6 烷基等、 Y 代表 C1-6 烷基等；以及 n 是 0 至 4 的整数； 或其盐。