ethyl 4-(4-cyanophenyl)-3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate | 1415400-50-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: ethyl 4-(4-cyanophenyl)-3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
• CAS: 1415400-50-8
• 化学式: C₂₄H₂₀N₄O₂
• 分子量: 396.448
• InChiKey: RRSWUQHYODLIPN-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  5-氨基-3-甲基-1-苯基吡唑 、 乙酰乙酸乙酯 、 4-氰基苯甲醛 反应 7.0h， 以73%的产率得到ethyl 4-(4-cyanophenyl)-3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
  参考文献：
  名称：

  An Efficient One-Step Synthesis of 1H-pyrazolo[3,4-b]pyridines in Basic Ionic Liquid [bmim]OH

  摘要：

  Chain 1,3-dicarbonyl compounds were firstly used as starting material to react with 5-amino-3-methyl-1- phenylpyrazol and aromatic aldehydes to prepare 1H-pyrazolo[3,4-b]pyridines in basic ionic liquid [bmim]OH. The onestep three-component reaction is simple and efficient. Additionally, water was the only one by-product during the whole process.

  DOI：

  10.2174/157017812803521144