[Cu(1,4-di(2-hydroxybenzylidene)thiosemicarbazide-2H)(H2O)2] | 752205-66-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [Cu(1,4-di(2-hydroxybenzylidene)thiosemicarbazide-2H)(H2O)2]
• 英文别名: copper;2-[(E)-[(E)-(2-oxidophenyl)methylideneamino]carbamothioyliminomethyl]phenolate;dihydrate
• CAS: 752205-66-6
• 化学式: C₁₅H₁₅CuN₃O₄S
• 分子量: 396.914
• InChiKey: GTSFMOXJNIBFEJ-PHRBSVTJSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  copper(II) choride dihydrate 、 N,N'-bis(salicylidene)thiosemicarbazide 在 LiOH*H₂O 作用下， 以 甲醇 、 水 为溶剂， 以84%的产率得到[Cu(1,4-di(2-hydroxybenzylidene)thiosemicarbazide-2H)(H2O)2]
  参考文献：
  名称：

  Mixed‐Ligand Complexes of a Schiff Base, 8‐Hydroxyquinoline and Oxalic Acid with Cu(II), Ni(II), Zn(II), and Fe(III) Ions: Pyrolytic Products and Biological Activities

  摘要：

  Binary mononuclear complexes of the Schiff base ligand 1,4-di(hydroxybenzylidene)thiosemicarbizide (H2L) and the transition metal ions Cu(II), Ni(II), Zn(H), and Fe(III) were prepared in the presence of various molar ratios of LiOH The binary complexes react with 8-hydroxyquinoline (8-HOqu) and oxalic acid (H(2)Ox) to form mixed-ligand complexes. The mixed ligand complexes were prepared by using various molar ratios of LiOH. The thermal Studies explored the stability of the mixed-ligands in their complexes as the isolated thermal products also contain the mixed ligands. All of the binary and mixed-ligand complexes have octahedral configurations except [CuHL]Cl and [ZnL], which have square-planar I geometrics. The Schiff base ligand (H2L) is coordinated to the central metal atom as a neutral, rnonoanionic and/or dianionic tetradentate ONNO ligand in the binary complexes and in the mixed-ligand complexes. The mixed-ligand, 8-HOqu behaves as a neutral or rnonoanionic bidentate ligand. The oxalato ligand coordinates as a dianionic bidentate or a bridged bidentate ligand towards Fe(Ill) ions. All complexes and the corresponding thermal products were isolated and their structures were elucidated by elemental analyses, conductance. IR and electronic absorption spectra. magnetic moments, H-1 NMR and TG-DSC measurements as well as by mass spectroscopy. The free ligand and H2L and its metal complexes showed higher antibacterial activity than some of, the investigated antibiotics, doxycillin, sulperazon, septrin, cefobid, nitrofurantion, and erythromycin.

  DOI：

  10.1081/sim-120028300