2-Formyloxy-methyl-anthrachinon | 92796-05-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 2-Formyloxy-methyl-anthrachinon
• 英文别名: (9,10-Dioxoanthracen-2-yl)methyl formate
• CAS: 92796-05-9
• 化学式: C₁₆H₁₀O₄
• 分子量: 266.253
• InChiKey: UWFSVTJNFCJIJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  60.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Photopatternable molecular circuitry
  申请人：——

  公开号：US20040122233A1

  公开（公告）日：2004-06-24

  Bistable molecules are provided with at least one photosensitive functional group. As thus constituted, the bistable molecules are photopatternable, thereby allowing fabrication of micrometer-scale and nanometer-scale circuits in discrete areas without relying on a top conductor as a mask. The bistable molecules may comprise molecules that undergo redox reactions, such as rotaxanes and catenanes, or may comprise molecules that undergo an electric-field-induced band gap change that causes the molecules, or a portion thereof, to rotate, bend, twist, or otherwise change from a substantially fully conjugated state to a less conjugated state. The change in states in the latter case results in a change in electrical conductivity.

  双稳态分子具有至少一个光敏功能基团。因此构成的双稳态分子是可光图案化的，从而可以在离散区域制备微米尺度和纳米尺度电路，而无需依赖顶部导体作为掩模。双稳态分子可能包括发生氧化还原反应的分子，例如轮烷和猫烷，或可能包括发生电场诱导的带隙变化的分子，导致分子或其中一部分旋转、弯曲、扭曲或以其他方式从基本完全共轭状态变为较少共轭状态。在后一种情况下，状态的变化导致电导率的变化。
• [EN] PHOTO-SWITCHABLE CHEMICAL INDUCERS OF DIMERIZATION FOR CONTROL OF PROTEIN FUNCTION IN CELLS BY LIGHT<br/>[FR] INDUCTEURS CHIMIQUES DE DIMÉRISATION PHOTO-COMMUTABLES POUR LA COMMANDE DE LA FONCTION DE PROTÉINES DANS DES CELLULES PAR DE LA LUMIÈRE
  申请人：MAX PLANCK GESELLSCHAFT

  公开号：WO2019008175A1

  公开（公告）日：2019-01-10

  The present application refers to photo-switchable chemical inducers of dimerization of formula (I) for control of protein interactions in cells by light. A compound, a test system, methods and uses are disclosed how the invention can be applied in the investigation of intracellular protein interactions. The system is composed of a compound of the general formula (I) as the photo-caged dimerizer, with the ability to covalently bind to HaloTag and a high affinity binding to eDHFR, respectively. The system can be activated and deactivated selectively on illumination with light under different irradiation conditions. Hal-(CH2)6-F1-P-F2-E ( I ).

  本申请涉及一种光开关化学二聚体诱导剂(I)的应用，用于通过光控制细胞中的蛋白质相互作用。本发明揭示了一种化合物、测试系统、方法和用途，以说明该发明如何应用于细胞内蛋白质相互作用的研究。该系统由一般式(I)的化合物作为光遮蔽二聚体化剂组成，具有与HaloTag的共价结合能力和与eDHFR的高亲和力结合能力。该系统可以在不同的照射条件下有选择地被光激活和去活化。Hal-(CH2)6-F1-P-F2-E (I)。
• Methods for reducing non-specific binding to an oligonucleotide array
  申请人：——

  公开号：US20010049108A1

  公开（公告）日：2001-12-06

  The present invention provides a variety of methods for reducing non-specific binding of a target molecule or plurality of target molecules to an array of oligonucleotides. The methods of the present invention include surface modification techniques and oligonucleotide modification techniques. According to one method of the present invention, non-specific binding of a target molecule to an array of oligonucleotides is reduced by replacing at least one of: i) the protecting groups on each of the plurality of oligonucleotides, and ii) the protecting groups on each of the protected regions of the substrate, with a negatively charged phosphate residue.

  本发明提供了多种减少目标分子或多个目标分子与寡核苷酸阵列非特异性结合的方法。本发明的方法包括表面修饰技术和寡核苷酸修饰技术。根据本发明的一种方法，通过用带负电荷的磷酸残基取代以下至少一种，可减少目标分子与寡核苷酸阵列的非特异性结合：i）多个寡核苷酸中每个寡核苷酸上的保护基团；ii）底物的每个保护区上的保护基团。
• EP1071821A4
  申请人：——

  公开号：EP1071821A4

  公开（公告）日：2005-06-29
• METHODS FOR REDUCING NON-SPECIFIC BINDING TO A NUCLEIC ACID PROBE ARRAY
  申请人：Affymetrix, Inc. (a California Corporation)

  公开号：EP1071821A1

  公开（公告）日：2001-01-31