{(3S,4S,4aS,7R)-7-[(S)-5-((R)-2-Benzyloxy-1-methyl-ethyl)-2-methyl-cyclopent-1-enylmethyl]-4,7-dimethyl-3,4,4a,5,6,7-hexahydro-cyclopenta[c]pyran-3-yloxy}-trimethyl-silane | 117182-71-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: {(3S,4S,4aS,7R)-7-[(S)-5-((R)-2-Benzyloxy-1-methyl-ethyl)-2-methyl-cyclopent-1-enylmethyl]-4,7-dimethyl-3,4,4a,5,6,7-hexahydro-cyclopenta[c]pyran-3-yloxy}-trimethyl-silane
• 英文别名: [(3S,4S,4aS,7R)-4,7-dimethyl-7-[[(5S)-2-methyl-5-[(2R)-1-phenylmethoxypropan-2-yl]cyclopenten-1-yl]methyl]-4,4a,5,6-tetrahydro-3H-cyclopenta[c]pyran-3-yl]oxy-trimethylsilane
• CAS: 117182-71-5
• 化学式: C₃₀H₄₆O₃Si
• 分子量: 482.779
• InChiKey: HVQHRZHSYIZLCZ-GFDXUBCRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  34
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  {(3S,4S,4aS,7R)-7-[(S)-5-((R)-2-Benzyloxy-1-methyl-ethyl)-2-methyl-cyclopent-1-enylmethyl]-4,7-dimethyl-3,4,4a,5,6,7-hexahydro-cyclopenta[c]pyran-3-yloxy}-trimethyl-silane 以93%的产率得到
  参考文献：
  名称：

  KATO, NOBUO;TANAKA, SHINYA;KATAOKA, HIDEO;TAKESHITA, HITOSHI, CHEM. LETT.,(1987) N 12, 2295-2298

  摘要：

  DOI：
• 作为产物：
  描述：

  [(1S,3S,4S,4aS)-4,7-dimethyl-1-[(1R,3S)-1-methyl-2-methylidene-3-[(2R)-1-phenylmethoxypropan-2-yl]cyclopentyl]-1,3,4,4a,5,6-hexahydrocyclopenta[c]pyran-3-yl]oxy-trimethylsilane 生成 {(3S,4S,4aS,7R)-7-[(S)-5-((R)-2-Benzyloxy-1-methyl-ethyl)-2-methyl-cyclopent-1-enylmethyl]-4,7-dimethyl-3,4,4a,5,6,7-hexahydro-cyclopenta[c]pyran-3-yloxy}-trimethyl-silane
  参考文献：
  名称：

  KATO, NOBUO;TAKESHITA, HITOSHI;TANAKA, SHINYA;KATAOKA, HIDEO, J. CHEM. SOC. PERKIN TRANS. PT 1,(1989) N0, C. 1833-1840

  摘要：

  DOI：

文献信息

• Total Synthesis of Dictymal, a B-seco-Dictymenoid Aldehyde from an Alga,<i>Diatyota diohotoma</i>
  作者：Nobuo Kato、Shinya Tanaka、Hideo Kataoka、Hitoshi Takeshita

  DOI：10.1246/cl.1987.2295

  日期：1987.12.5

  A B-seco-dictymenoid aldehyde, dictymal, was synthesized from two optically active iridoid synthons; the required ring system was constructed by lactol-regulated Cope rearrangement and stereoselective Li-tert-BuOH-in-HMPA reduction of the tetrasubstituted C=C.

  B-seco-dictymenoid 醛, dictymal, 是由两个旋光环烯醚合成子合成的；所需的环系统是通过乳醇调节的 Cope 重排和立体选择性 Li-tert-BuOH-in-HMPA 还原四取代 C=C 构建的。