4-[2-(甲氧羰基)-4-吡啶基]苯甲酸 | 351435-26-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 4-[2-(甲氧羰基)-4-吡啶基]苯甲酸
• 中文别名: 2-(4-氯-2-甲基苯氧基)丙酸盐钙
• 英文名称: 4-(2-(Methoxycarbonyl)pyridin-4-yl)benzoic acid
• 英文别名: 4-(2-methoxycarbonylpyridin-4-yl)benzoic acid
• CAS: 351435-26-2
• 化学式: C₁₄H₁₁NO₄
• 分子量: 257.24
• InChiKey: QWUROVBYWLRREV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  76.5
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• COMPOUNDS EXHIBITING THROMBOPOIETIN RECEPTOR AGONISM
  申请人：TAKEMOTO Hiroshi

  公开号：US20100022542A1

  公开（公告）日：2010-01-28

  Pharmaceutical compositions containing as an active ingredient compounds of the general formula (I), prodrugs of the same, pharmaceutically acceptable salts of both, or solvates of them and exhibiting thrombopoietin receptor agonism: X 1 —Y 1 -Z 1 -W 1 (I) wherein X 1 is optionally substituted aryl, optionally substituted heteroaryl or the like; Y 1 is —NR A CO—(CH 2 ) 0-2 — or the like (wherein R A is a hydrogen or the like); Z 1 is optionally substituted phenylene or the like; and W 1 is a group represented by the below formula: wherein R 1 , R 2 , R 3 , and R 4 are each independently a hydrogen atom, optionally substituted lower alkyl or the like, a broken line (---) represents the presence or absence of bond.
• US7582665B2
  申请人：——

  公开号：US7582665B2

  公开（公告）日：2009-09-01