4-(1-phenyl-1-methylcyclobutane-3-yl)-2-(2-hydroxy-5-bromo)benzylideneaminothiazole | 283604-99-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-(1-phenyl-1-methylcyclobutane-3-yl)-2-(2-hydroxy-5-bromo)benzylideneaminothiazole
• CAS: 283604-99-9
• 化学式: C₂₁H₁₉BrN₂OS
• 分子量: 427.365
• InChiKey: IZPIXHDOGZXHOU-WEHONNDLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  26.0
• 可旋转键数：
  4.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  45.48
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  4-(1-phenyl-1-methylcyclobutane-3-yl)-2-(2-hydroxy-5-bromo)benzylideneaminothiazole 、 nickel(II) acetate tetrahydrate 以 甲醇 为溶剂， 以74%的产率得到
  参考文献：
  名称：

  Synthesis and Characterization of a New Cyclobutane-Substituted Schiff Base Ligand and its Co(II), Cu(II) and Ni(II) Complexes

  摘要：

  A new ligand, 4-(1-phenyl-1-methylcyclobutane-3-yl)-2-(2-hydroxy-5-bromo)benzylideneaminothiazole (LH), has been synthesized starting from 1-phenyl-1-methyl-3-(2-chloro-1-oxoethyl)cyclobutane, thiourea and 2-hydroxy-5-bromobenzaldehyde. Mononuclear complexes with a metal-ligand ratio of 1:2 have been prepared with Co(II), Cu(II), and Ni(II). Attempts to prepare the Cd(II) complex of the ligand in different solvents have failed. The authenticity of the ligand and its complexes was established based on elemental analyses, IR, C-13 and H-1 NMR spectra, UV-Vis, magnetic susceptibility measurements and thermogravimetric analyses (TGA).

  DOI：

  10.1080/00945710009351803