[Ru(2,2′-bipyridine)2(4,4″-azobis (2,2′-bipyridine))Ru(2,2′-bipyridine)2] | 183311-66-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: [Ru(2,2′-bipyridine)2(4,4″-azobis (2,2′-bipyridine))Ru(2,2′-bipyridine)2]
• 英文别名: [Ru(bpy)2(azobpy)Ru(bpy)2]；[Ru(2,2'-bipyridine)2(μ-5,5''-azobis(2,2'-bipyridine))Ru(2,2'-bipyridine)2](4+)；Bis(2-pyridin-2-ylpyridin-4-yl)diazene;2-pyridin-2-ylpyridine;ruthenium(2+)
• CAS: 183311-66-2
• 化学式: C₆₀H₄₆N₁₄Ru₂
• 分子量: 1165.26
• InChiKey: SCWZQEZJALPJBG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.59
• 重原子数：
  76
• 可旋转键数：
  8
• 环数：
  12.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  179
• 氢给体数：
  0
• 氢受体数：
  14

反应信息

• 作为产物：
  描述：

  在 四丁基高氯酸铵 作用下， 以 乙腈 为溶剂， 生成 [Ru(2,2′-bipyridine)2(4,4″-azobis (2,2′-bipyridine))Ru(2,2′-bipyridine)2]
  参考文献：
  名称：

  Colorimetric and luminescent dual-signaling responsive probing of thiols by a ruthenium(II)-azo complex

  摘要：

  A dinuclear ruthenium(II) complex linked via a reducible azo group [Ru(bpy)(2)(azobpy)Ru(bpy)(2)]Cl-4 (Ru(2)azo, bpy=2,2'-bipyridine, azobpy=4,4 ''-azobis (2,2'-bipyridine)) was adopted as a probe for thiols. Results showed that Ru(2)azo could selectively and effectively react with biological thiols (such as cysteine, homocysteine and glutathione) with a 10(-7) M detection limit. After it reacted with thiols, the original gray color of Ru(2)azo solution immediately turned yellow and the luminescence significantly enhanced, showing "naked-eye" colorimetric and "off-on" luminescent dual-signaling response for thiols. Mechanism studies demonstrated that Ru(2)azo reacted with thiols undergoing a two-electron transfer process, forming the azo(2-) anion product. (c) 2013 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.jinorgbio.2012.12.019