2-vinyl-1H-benzo[f]isoindole-1,3(2H)-dione | 1085337-04-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-vinyl-1H-benzo[f]isoindole-1,3(2H)-dione
• 英文别名: 2-Ethenylbenzo[f]isoindole-1,3-dione
• CAS: 1085337-04-7
• 化学式: C₁₄H₉NO₂
• 分子量: 223.231
• InChiKey: JWLBNNOTEZIFRR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-叠氮丙二酸二甲酯 、 2-vinyl-1H-benzo[f]isoindole-1,3(2H)-dione 在 bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]} 作用下， 以 二氯甲烷 为溶剂， 反应 26.0h， 以94%的产率得到dimethyl 2-(1,3-dioxo-1H-benzo[f]isoindol-2(3H)-yl)cyclopropane-1,1-dicarboxylate
  参考文献：
  名称：

  Catalytic Friedel–Crafts Reaction of Aminocyclopropanes

  摘要：

  A Lewis acid catalyzed Friedel-Crafts reaction between donor-acceptor aminocyclopropanes and indoles and other electron-rich aromatic compounds is reported. Indole alkylation at the C3 position was generally obtained for a broad range of functional groups and substitution patterns. In the case of C3-substituted indoles, C2 alkylation was observed. The reaction gives a rapid access to gamma amino acid derivatives present in numerous bioactive molecules.

  DOI：

  10.1021/ol401616a
• 作为产物：
  描述：

  2，3-萘二酐 在 formamide 、 lithium chloride 、 palladium dichloride 作用下， 反应 31.01h， 生成 2-vinyl-1H-benzo[f]isoindole-1,3(2H)-dione
  参考文献：
  名称：

  碘配体辅助双核 Pd(I)-Pd(I) 催化烯烃和炔烃的选择性加氢甲酰化

  摘要：

  自 1938 年被发现以来，加氢甲酰化得到了彻底的研究并在工业中得到了广泛的应用（每年超过 107 公吨）。然而，迄今为止，使用成熟的 Rh 或助催化剂精确控制其区域选择性的能力已被证明是难以捉摸的，从而限制了许多具有合成价值的醛的获得。钯催化剂代表了一种有吸引力的替代品，但由于不希望的副加工，它们的使用仍然很少。在这里，我们报告了一种高选择性和异常活性的催化剂系统，该系统由一种新型活化策略驱动，并具有独特的 Pd(I)-Pd(I) 机制，涉及碘化物辅助双核步骤以释放产物。这种方法能够对大范围的烯烃和炔烃（包括敏感的起始材料）进行 β 选择性加氢甲酰化。它的效用在抗肥胖药物利莫那班和抗 HIV 药物 PNU-32945 的合成中得到了证明。在更广泛的背景下，新的机理理解使其他对化学工业具有重要意义的羰基化反应的发展成为可能。

  DOI：

  10.1021/jacs.0c09254

文献信息

• OPTICAL COMPENSATION FILMS WITH BIREFRINGENCE ENHANCING SUBSTITUENTS FOR LIQUID CRYSTAL DISPLAY
  申请人：Akron Polymer Systems

  公开号：EP2137222B1

  公开（公告）日：2014-07-23
• Optical compensation films with mesogen groups for liquid crystal display
  申请人：Zhang Dong

  公开号：US20080237552A1

  公开（公告）日：2008-10-02

  Optical compensation films (positive C-plate) with mesogen anisotropic subunits (OASUs) that have high positive birefringence throughout the wavelength range 400 nm<λ<800 nm are provided. The optical compensation films may be processed by solution casting to yield a polymer film with high birefringence without the need for stretching, photopolymerization, or other processes. Such optical compensation films are suitable for use as a positive C-plate in LCDs, particularly IPS-LCDs.
• Optical compensation films having positive birefringence for liquid crystal display
  申请人：Zheng Xiaoliang Joe

  公开号：US20080239491A1

  公开（公告）日：2008-10-02

  A method for controlling positive birefringence in an optical compensation film (positive C-plate) having high positive birefringence throughout the wavelength range 400 nm<λ<800 nm is provided. The method includes selecting polymers with optically anisotropic subunits (OASUs) that exhibit the buttressing effect, wherein the OASUs may be disks, mesogens or aromatic rings substituted with birefringence enhancing substituents. The method further includes processing the polymer by solution casting to yield a polymer film with high birefringence without the need for stretching, photopolymerization, or other processes. These optical compensation films may be used in LCDs, particularly IPS-LCDs.
• Liquid crystal display having improved wavelength dispersion characteristics
  申请人：Harris Frank W.

  公开号：US20080241427A1

  公开（公告）日：2008-10-02

  A multilayer optical retardation compensation film having at least one positive C-plate and at least one negative C-plate is used in an LCD device. The multilayer film may have a substantially flat wavelength dispersion curve, or the multilayer film combined with other layers in the LCD device may have a substantially flat wavelength dispersion curve. Polymer films for the positive C-plate may be identified according to their absorbance maxima at certain wavelength ranges.
• Optical compensation films with disk groups for liquid crystal display
  申请人：Harris Frank W.

  公开号：US20080241428A1

  公开（公告）日：2008-10-02

  Optical compensation films (positive C-plate) with disk anisotropic subunits (OASUs) that have high positive birefringence throughout the wavelength range 400 nm<λ<800 nm are provided. The optical compensation films may be processed by solution casting to yield a polymer film with high birefringence without the need for stretching, photopolymerization, or other processes. Such optical compensation films are suitable for use as a positive C-plate in LCDs, particularly IPS-LCDs.