2,2'-methylene-dicyclohexyl-diamine | 70906-77-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2,2'-methylene-dicyclohexyl-diamine
• 英文别名: 2,2'-methylene-dicyclohexyldiamine；2,2'-diaminodicyclohexylmethane；2,2'-dicyclohexylmethanediamine；Bis-<2-amino-cyclohexyl>-methan；Bis-(2-amino-cyclohexyl)-methan；2-[(2-Aminocyclohexyl)methyl]cyclohexan-1-amine
• CAS: 70906-77-3
• 化学式: C₁₃H₂₆N₂
• 分子量: 210.363
• InChiKey: VYAFHUCZHUIBPY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2921300090

反应信息

• 作为反应物：
  描述：

  2,4-methylene-dicyclohexyl-diamine 、 4,4'-二氨基二环己基甲烷 、 2,2'-methylene-dicyclohexyl-diamine 、 尿素 、 正丁醇 220.0 ℃ 、1.4 MPa 条件下， 反应 8.5h， 生成 二丁基(亚甲基二-4,1-环己烷二基)二氨基甲酸酯
  参考文献：
  名称：

  Multistage continuous preparation of cycloaliphatic diisocyanates

  摘要：

  一种连续无光气制备环状脂肪族二异氰酸酯的工艺。

  公开号：

  US20050043561A1
• 作为产物：
  描述：

  2-[(4-氨基苯)甲基]苯胺 、 2,2'-亚甲基二苯胺 、 N-甲基-4,4′-甲撑二苯胺 、 4,4'-二氨基二苯甲烷 在 ruthenium on aluminium oxide 氢气 作用下， 以 甲醇 为溶剂， 生成 (2R,4R,5R,6S)-2,5-二(羟甲基)-6-(哌啶-3-氧基)二氢-2H-吡喃-2,3,3,4,5(4H)-五唑(non-preferredname) 、 4-[[4-(甲基氨基)环己基]甲基]环己烷-1-胺 、 4,4'-二氨基二环己基甲烷 、 2,2'-methylene-dicyclohexyl-diamine
  参考文献：
  名称：

  [EN] PROCESS FOR INCREASING THE SELECTIVITY OF THE HYDROGENATION OF 4,4'-DIAMINODIPHENYLMETHANE TO 4,4'-DIAMINODICYCLOHEXYLMETHANE IN THE PRESENCE OF AN N-ALKYL-4,4'-DIAMINODIPHENYLMETHANE
  [FR] PROCEDE D'AUGMENTATION DE LA SELECTIVITE DE L'HYDROGENATION DE 4,4'-DIAMINODIPHENYLMETHANE EN 4,4'-DIAMINODICYCLOHEXYLMETHANE EN PRESENCE D'UN N-ALKYL-4,4'-DIAMINODIPHENYLMETHANE

  摘要：

  公开号：

  WO2004007425A3

文献信息

• CATALYST FOR PRODUCING N-SUBSTITUTED CARBAMATES, AND THE PREPARATION AND APPLICATION OF THE SAME
  申请人：Wershofen Stefan

  公开号：US20100298592A1

  公开（公告）日：2010-11-25

  The present invention relates to a novel catalyst for producing N-substituted carbamates, the preparation of the catalyst and an improved method for producing N-substituted carbamates from these novel catalysts. The active component of the catalyst is a heteropoly acid and the catalyst support comprises a metal oxide or a metalloid oxide. The catalyst can be used to promote the reaction of carbamate and amine, thereby generating N-substituted carbamates with high yield. In the presence of the catalyst, the reaction conditions are relatively mild, the catalytic activity and selectivity of the reaction are high, and the reaction time is relatively short. Furthermore, the catalyst can be conveniently separated from the reaction system and recycled. therefore, the catalyst can be used to facilitate the further scale-up test and commercial application.

  本发明涉及一种用于生产N-取代氨基甲酸酯的新型催化剂，包括催化剂的制备和从这些新型催化剂生产N-取代氨基甲酸酯的改进方法。催化剂的活性成分是杂多酸，催化剂载体包括金属氧化物或金属氧化物。催化剂可用于促进氨基甲酸酯和胺的反应，从而高产率地生成N-取代氨基甲酸酯。在催化剂存在的情况下，反应条件相对温和，反应的催化活性和选择性高，反应时间相对较短。此外，催化剂可以方便地从反应体系中分离并回收。因此，该催化剂可用于促进进一步的放大试验和商业应用。
• PROCESS FOR THE CONTINUOUS PREPARATION OF (CYCLO)ALIPHATIC DIISOCYANATES
  申请人：Michalczak Hans-Werner

  公开号：US20100036154A1

  公开（公告）日：2010-02-11

  The invention relates to a multi-stage process for the continuous, phosgene-free preparation of (cyclo)aliphatic diisocyanates that comprises the conversion of (cyclo)aliphatic diamines into the corresponding (cyclo)alkylene biscarbamates and the thermal cleaving of the latter into the (cyclo)alkylene diisocyanates and alcohol. The urea used in accordance with the invention and also the urea employed for the preparation of urea equivalents (e.g. alkyl carbonates, alkyl carbamates) as a possible precursor for the synthesis of the (cyclo)aliphatic biscarbamates is unconditioned.

  本发明涉及一种多级连续、无光气制备（环）脂肪族二异氰酸酯的方法，包括将（环）脂肪族二胺转化为相应的（环）烷基双氨基甲酸酯，然后将其热解为（环）烷基二异氰酸酯和醇的过程。本发明所使用的尿素以及用于制备尿素等效物（例如烷基碳酸酯、烷基氨基甲酸酯）的尿素作为合成（环）脂肪族双氨基甲酸酯的可能前体，均为未经处理的。
• LOW MOLECULAR WEIGHT PRODUCTS AND USE THEREOF AS REVERSIBLE OR PERMANENT LOW-TEMPERATURE CROSSLINKING AGENT IN DIELS-ALDER REACTIONS
  申请人：Schmidt Friedrich Georg

  公开号：US20140163165A1

  公开（公告）日：2014-06-12

  The invention relates to low molecular mass products and to the use thereof as reversible or permanent low-temperature crosslinkers in Diels-Alder reactions.

  本发明涉及低分子量产物及其作为Diels-Alder反应中可逆或永久低温交联剂的使用。
• LOW CHLORINE, MULTI-STAGED METHOD FOR PRODUCING CYCLOALIPHATIC DISOCYANATES
  申请人：Grund Gerda

  公开号：US20110028755A1

  公开（公告）日：2011-02-03

  Low chlorine, multi-staged method for producing cycloaliphatic diisocyanates. The invention relates to a multi-staged method for the continuous low-chlorine production of cycloaliphatic diisocyanates, comprising the synthesis of diaminodipheynl alkanes, the hydration thereof into the corresponding cycloaliphatic diamines and the subsequent conversion of cycloaliphatic diamines to the corresponding cycloalkylene biscarbamates and the thermal cleaving of the latter into the cycloaliphatic diisocyanates and alcohol.

  低氯多级生产环烷二异氰酸酯的方法。本发明涉及一种多级方法，用于连续低氯生产环烷二异氰酸酯，包括合成二氨基二苯基烷烃，将其水化为相应的环烷基二胺，然后将环烷基二胺转化为相应的环烷基二氨基甲酸酯，最后将其热解为环烷二异氰酸酯和醇。
• METHOD FOR PREPARING DIAMINO-DICYCLOHEXYL METHANE
  申请人：WANHUA CHEMICAL GROUP CO., LTD.

  公开号：US20160068472A1

  公开（公告）日：2016-03-10

  Disclosed is a method for preparing diamino-dicyclohexyl methane (H 12 MDA) by hydrogenation of diamino-diphenyl methane (MDA). In the process, 4,4′-MDA used as the starting material is firstly hydrogenated to prepare 4,4′-H 12 MDA. When the activity of the catalyst is reduced, the feed is switched from 4,4′-MDA to the mixture of 2,4′-MDA and 4,4′-MDA, and then when the conversion is stabilized, the feed is switched to 4,4′-MDA again. The deactivated catalyst is activated on line by switching the feed to the mixture of 2,4′-MDA and 4,4′-MDA. 4,4′-H 12 MDA having the trans-trans isomer content of 16˜24 wt % is produced, and the mixture of 2,4′-H 12 MDA and 4,4′-H 12 MDA is also produced, wherein the content of 2,4′-H 12 MDA in the mixture is 4˜15 wt %.

  本发明公开了一种通过氢化二氨基二苯甲烷（MDA）制备二氨基二环己基甲烷（H12MDA）的方法。在该过程中，首先将起始材料4,4'-MDA氢化制备4,4'-H12MDA。当催化剂活性降低时，将进料从4,4'-MDA切换到2,4'-MDA和4,4'-MDA的混合物，当转化稳定后，再将进料切换回4,4'-MDA。失活的催化剂通过将进料切换到2,4'-MDA和4,4'-MDA的混合物上线活化。制备出具有16~24重量％的顺式-顺式异构体含量的4,4'-H12MDA，以及2,4'-H12MDA和4,4'-H12MDA的混合物，其中混合物中2,4'-H12MDA的含量为4~15重量％。