2-(2-Carbamoyl-benzyl)-pyridin | 7547-83-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2-Carbamoyl-benzyl)-pyridin
• 英文别名: 2-pyridin-2-ylmethyl-benzamide；Picolylbenzamide；2-(pyridin-2-ylmethyl)benzamide
• CAS: 7547-83-3
• 化学式: C₁₃H₁₂N₂O
• 分子量: 212.251
• InChiKey: AIZIIROOYVPSIM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  56
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] CATALYTIC HYDROGENATION OF SUBSTITUTED CYANOPYRIDINES AND PROCESS FOR PREPARING SUBSTITUTED PYRIDYLMETHYLBENZAMIDES<br/>[FR] HYDROGÉNATION CATALYTIQUE DE CYANOPYRIDINES SUBSTITUÉES ET PROCÉDÉ DE PRÉPARATION DE PYRIDYLMÉTHYLBENZAMIDES SUBSTITUÉS
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2016173998A1

  公开（公告）日：2016-11-03

  The present invention relates to novel processes for the preparation of substituted pyridyl- methylbenzamide derivatives of formula (I), in particular 2,6-dichloro-N- [3-chloro-5-(trifluoromethyl)- 2-pyridyl]methyl}benzamide (Fluopicolide), and for the catalytic hydrogenation of substituted cyanopyridine derivatives, in particular 3-chloro-2-cyano-5-trifluoromethylpyridine [= Py-CN] to the corresponding substituted 2-methylaminopyridine derivatives, in particular 2-aminomethyl-3-chloro-5- trifluoromethylpyridine [= Py-methylamine] or salts thereof in the presence of metal catalysts such as in particular palladium catalysts, catalytic modifiers and acids.

  本发明涉及制备取代吡啶基-甲基苯甲酰胺衍生物的新工艺，特别是2,6-二氯-N- [3-氯-5-(三氟甲基)-2-吡啶基]甲基}苯甲酰胺（氟哌啶）的工艺，以及对取代氰基吡啶衍生物进行催化氢化的工艺，特别是3-氯-2-氰基-5-三氟甲基吡啶[= Py-CN]到相应的取代2-甲氨基吡啶衍生物，特别是2-氨基甲基-3-氯-5-三氟甲基吡啶[= Py-甲胺]或其盐在金属催化剂的存在下进行，特别是钯催化剂、催化改性剂和酸。
• [EN] FUNGICIDAL AMIDES<br/>[FR] AMIDES FONGICIDES
  申请人：FMC CORP

  公开号：WO2021146522A1

  公开（公告）日：2021-07-22

  Disclosed are compounds of Formula 1 including all geometric and stereoisomers, N-oxides, and salts thereof, (I) wherein Z, X, R1, R2, W, R3, R4a, R4b, L, R5a, R5b and Q are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.

  公开的是Formula 1的化合物，包括所有的几何和立体异构体，N-氧化物和盐，其中Z、X、R1、R2、W、R3、R4a、R4b、L、R5a、R5b和Q的定义如披露所述。还公开了含有Formula 1化合物的组合物，以及用于控制由真菌病原体引起的植物疾病的方法，包括施用本发明的化合物或组合物的有效量。
• Agrochemical Composition Comprising Pesticide and UV Absorber
  申请人：Misske Andrea

  公开号：US20110237665A1

  公开（公告）日：2011-09-29

  The present invention relates to an agrochemical composition comprising pesticide and UV absorber, and the abovementioned UV absorbers. The invention furthermore relates to the use of the UV absorbers in agrochemical compositions. It moreover relates to a method of controlling phytopathogenic fungi and/or undesirable plant growth and/or undesirable insect or mite infestation and/or of regulating plant growth.

  本发明涉及一种包括杀虫剂和紫外线吸收剂的农药组合物，以及上述紫外线吸收剂。此外，该发明还涉及在农药组合物中使用紫外线吸收剂。此外，它还涉及一种控制植物病原真菌和/或不良植物生长和/或不良昆虫或螨虫侵袭和/或调节植物生长的方法。
• [EN] PROCESS FOR THE PREPARATION OF FLUOPICOLIDE<br/>[FR] PROCÉDÉ DE PRÉPARATION DE FLUOPICOLIDE
  申请人：BAYER AG

  公开号：WO2019101769A1

  公开（公告）日：2019-05-31

  The present invention relates to an improved process for the preparation of substituted pyridylmethyl- benzamide derivatives of formula (I), in particular 2,6-Dichloro-N-[3-chloro-5-(trifluoromethyl)-2- pyridyl]methyl}benzamide (Fluopicolide), from substituted 2-(Aminomethyl)pyridine derivatives which are obtained by Raney-Nickel hydrogenation.

  本发明涉及一种改进的方法，用于制备配方（I）的取代吡啶甲基苯甲酰衍生物，特别是2,6-二氯-N-[3-氯-5-(三氟甲基)-2-吡啶基]甲基}苯甲酰胺（氟哌啶酰胺），该方法使用经Raney-Nickel氢化得到的取代2-(氨甲基)吡啶衍生物。
• Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof
  申请人：REICH Melanie

  公开号：US20090069320A1

  公开（公告）日：2009-03-12

  Substituted 4-amino-quinazoline compounds corresponding to formula I methods for their production, pharmaceutical compositions containing these compounds as active agents, and the uses thereof for treating or inhibiting disorders or disease states.

  根据公式I的4-氨基喹唑啉化合物替代物，其生产方法，含有这些化合物的药物组合物以及用于治疗或抑制疾病状态或疾病状态的用途。