4-乙氧基-N-异丙基苯甲酰胺 | 349109-70-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-乙氧基-N-异丙基苯甲酰胺
• 英文名称: 4-ethoxy-N-propan-2-ylbenzamide
• CAS: 349109-70-2
• 化学式: C₁₂H₁₇NO₂
• mdl: MFCD01216122
• 分子量: 207.27
• InChiKey: BAKNOHIYRHDNQD-UHFFFAOYSA-N

物化性质

• 沸点：
  352.7±25.0 °C(Predicted)
• 密度：
  1.017±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.416
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS
  申请人：Tao Chunlin

  公开号：US20120172361A1

  公开（公告）日：2012-07-05

  Compounds of the formula (I) and formula (II) and pharmaceutically acceptable salts thereof.

  公式（I）和公式（II）的化合物及其药学上可接受的盐。
• Inhibitors of Base Excision Repair Activity and Therapeutic Methods Based Thereon
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：US20200190034A1

  公开（公告）日：2020-06-18

  Noncovalent small-molecule inhibitors of the enzyme OGG1, methods of their manufacture, and applications for their administration are provided. Small molecule inhibitors were shown to be selective for inhibiting OGG1 over multiple repair enzymes, including other base excision repair enzymes, and it displayed no toxicity in two human cell lines. The inhibitors provide a tool for the study of the role of OGG1 in multiple disease-related pathways, and a therapeutic target for the treatment thereof.