4-乙炔基-2-甲基苯胺 | 146141-31-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-乙炔基-2-甲基苯胺
• 中文别名: 苯胺,4-乙炔基-2-甲基-(9CI)
• 英文名称: 2-methyl-4-ethynylaniline
• 英文别名: 4-Ethynyl-2-methylaniline
• CAS: 146141-31-3
• 化学式: C₉H₉N
• 分子量: 131.177
• InChiKey: WDNCVJZQRADJNX-UHFFFAOYSA-N

物化性质

• 沸点：
  246.4±33.0 °C(Predicted)
• 密度：
  1.03±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-乙炔基-2-甲基苯胺 在 triethylamine 作用下， 以 二氯甲烷 为溶剂， 生成 [Au(CCC6H3(Me-2)NH2-4)(P(C6H4OMe-4)3)]
  参考文献：
  名称：

  Gold(I) alkynyl complexes derived from ethynylanilines: crystal structure of [Au(CC-4-C6H4NH2){P(3-tolyl)3}] a polymer in the solid state via NH⋯Au contacts

  摘要：

  Reaction of [AuCl(SMe2)] with para-ethynylaniline and para-ethynyl-ortho-toluidine affords oligomers, [Au(C equivalent to C-4-C6H3RNH2)L] (R = H, Me), which in turn react with tertiary phosphines or 2,5-dimethylphenylisocyanide to give monomeric adducts, [Au(C equivalent to C-4-C6H3RNH2)L]. One of these, [Au(C equivalent to C-4-C6H4NH2){P(3-tolyl)(3)}], has been crystallographically characterised and is a polymer in the solid state, being held together via (NHAu)-Au-. . . contacts. (c) 2004 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2004.06.068

文献信息

• ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF
  申请人：Fujifilm Corporation

  公开号：EP2202220A1

  公开（公告）日：2010-06-30

  [Problem to be Solved] To provide an acetylene compound having a structure in which a unit having an amino group and a unit having an ethynyl group are bonded via a linking group, the acetylene compound being introducable to a polymer having thermal resistance. [Means for Solving the Problem] An acetylene compound represented by the following Formula (1) and a salt thereof: wherein in Formula (1), X represents a single bond or a divalent linking group; A represents a hydrocarbon group, a heteroaromatic ring or a heteroalicyclic compound; B represents a hydrocarbon group, a heteroaromatic ring, a heteroalicyclic compound or a single bond; R1 represents a hydrogen atom, a hydrocarbon group, a heteroaromatic ring, a heteroalicyclic compound or a silyl group; R4 represents a hydrogen atom or a group that can be a substituent of an amino group; and m, n and a each independently represent an integer of 1 or greater.

  解决的问题是提供一种乙炔化合物，其结构中含有通过连接基团连接的具有氨基团和乙炔基团的单元，该乙炔化合物可引入到具有热阻抗的聚合物中。解决问题的方法是通过以下式（1）表示的乙炔化合物及其盐：其中在式（1）中，X代表单键或二价连接基团；A代表烃基团、杂环芳香环或杂环脂环化合物；B代表烃基团、杂环芳香环、杂环脂环化合物或单键；R1代表氢原子、烃基团、杂环芳香环、杂环脂环化合物或硅基团；R4代表氢原子或可作为氨基团的取代基团；m、n和a分别独立表示大于或等于1的整数。
• PHOSPHORESCENT TRANSITION METAL COMPLEX, ITS PREPARATION AND USE
  申请人：City University of Hong Kong

  公开号：US20170114275A1

  公开（公告）日：2017-04-27

  A phosphorescent transition metal complex especially suitable as sensor for hydrogen peroxide in cells, in particular in mitochondria in live cells, includes a metallic central atom, which is a transition metal, a first ligand with at least one pyridine ring, and a second ligand having at least one pyridine ring and at least one structural component selected from the group of 1,2-diketone moiety and an arylboronate moiety. A method for preparing the metal complex is also disclosed as well as a method of detecting hydrogen peroxide in cells by incubating cells with the transition metal complex. The metal complex shows advantageous intense and long-lived phosphorescence accompanied by exceptional cellular localization properties. The metal complex is highly photostable and highly selective towards hydrogen peroxide, thus, especially suitable for detecting mitochondrial H 2 O 2 .

  一种磷光过渡金属配合物，特别适用于细胞中的过氧化氢传感器，特别是在活细胞中的线粒体中，包括一个金属中心原子，该原子是过渡金属，第一配体具有至少一个吡啶环，第二配体具有至少一个吡啶环和从1,2-二酮基团和芳基硼酸酯基团组中选择的至少一个结构组分。还公开了一种制备金属配合物的方法以及通过将细胞与过渡金属配合物孵育来检测细胞中的过氧化氢的方法。该金属配合物显示出优越的强烈和长寿命的磷光，并具有异常的细胞定位特性。该金属配合物具有高光稳定性和高选择性，因此特别适用于检测线粒体H2O2。
• 一种可回收套用的芳香胺试剂及其制备和应用
  申请人：浙江新和成股份有限公司

  公开号：CN113912551B

  公开（公告）日：2023-04-18

  本发明公开了一种可回收套用的芳香胺试剂及其制备和应用，该芳香胺试剂是利用3‑氯丙基三乙氧基硅烷作为反应的连接体，制备3‑叠氮丙基三乙氧基硅烷，通过点击化学得到取代芳香胺，将取代芳香胺通过连接体固载在介孔硅胶上得到，将该芳香胺试剂先与钠代盐反应，再与游离乙脒环合生成2‑甲基‑4‑氨基‑5‑甲酰胺甲基嘧啶，同时释放芳香胺试剂，并回收循环利用。本发明不使用高度致癌的邻氯苯胺或其它小分子苯胺化合物，杜绝了维生素B1产品中邻氯苯胺类化合物的残留。同时芳香胺试剂易回收、可循环，反应收率高。同时选用的固定化载体为介孔硅胶，价格低廉、比表面积大、表面有很多键合的硅羟基，所以适用于作载体。
• ACETYLENE COMPOUND
  申请人：Fujifilm Corporation

  公开号：EP2202221A1

  公开（公告）日：2010-06-30

  The invention provides an acetylene compound represented by the following Formula (1), which is useful as a raw material for a polymer achieving high thermal resistance; wherein, in Formula (1), the encircled Ar represents an aryl group or a heteroaryl group; X represents a divalent linking group; R, R' and R1 each independently represent a hydrogen atom, a hydrocarbon group or a heterocyclic group; R2 represents a hydrogen atom or a substituent substitutable on a benzene ring; A represents a hydrocarbon group or a heterocyclic group; Q represents a hydrogen atom, a hydrocarbon group, or a metal element capable of forming a monovalent metal salt; a represents an integer from 0 or more; b, m and n each independently represent an integer of 1 or more; when n, m and b are 1 at the same time, X is not -(C=O)O-; and when n is 2, and both m and b are 1, X is not -O-.

  本发明提供了一种由下式（1）表示的乙炔化合物，它可用作具有高耐热性的聚合物的原料； 其中，在式(1)中，环绕的 Ar 代表芳基或杂芳基；X 代表二价连接基团；R、R'和 R1 各自独立地代表氢原子、烃基或杂环基团；R2 代表氢原子或可取代苯环的取代基；A 代表烃基或杂环基团；Q代表氢原子、烃基或能形成一价金属盐的金属元素；a代表0或0以上的整数；b、m和n各自独立地代表1或1以上的整数；当n、m和b同时为1时，X不是-(C=O)O-；当n为2且m和b均为1时，X不是-O-。
• US9890327B2
  申请人：——

  公开号：US9890327B2

  公开（公告）日：2018-02-13