3β-hydroxy-11-oxo-21-nor-5α-pregnanoic acid-(20) | 74381-63-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3β-hydroxy-11-oxo-21-nor-5α-pregnanoic acid-(20)
• 英文别名: 3β-Hydroxy-11-oxo-5α-androstan-carbonsaeure-(17β)；3β-Hydroxy-11-oxo-21-nor-5α-pregnansaeure-(20)；(3S,5S,8S,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-11-oxo-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-17-carboxylic acid
• CAS: 74381-63-8
• 化学式: C₂₀H₃₀O₄
• 分子量: 334.456
• InChiKey: QAANIDZFOKGZHZ-GTRPQKJASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  24
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3β-hydroxy-11-oxo-21-nor-5α-pregnanoic acid-(20) 在 溶剂黄146 、 铂 作用下， 生成 3α,11α-dihydroxy-21-nor-5β.17βH-pregnanoic acid-(20)
  参考文献：
  名称：

  Behavioural observations of interactions in a free-ranging lynxLynx lynx family at kills

  摘要：

  The behaviour of a free-ranging female lynx Lynx lynx Linnaeus, 1758 and her kittens at 12 different kills was studied for 44 hours of observation from September 1996 to March 1997. The development of interactions at kills of a lynx family group showed the following pattern: until the end of September we often observed two lynx, usually both kittens, food from the kill at the same time. After the age of four months aggression between kittens was observed frequently, with the bigger kitten being dominant. From September the kittens were never again seen feeding together at the kill, However, we never observed fighting, and aggressive behaviour did not increase with the age of the, kittens. Whereas until December one of the kittens was always first at the kill, from January onwards it was mostly the adult female who ate first. She introduced her kittens to the home range of a neighbouring female where the family break-up occurred. The kittens were last seen together with their mother on 26 March. Dispersal seemed to be initiated by the female abandoning the kittens.

  DOI：

  10.1007/bf03192451
• 作为产物：
  描述：

  别孕甾烷-3beta,21-二醇-11,20-二酮 在 硫酸 、 过碘酸 作用下， 生成 3β-hydroxy-11-oxo-21-nor-5α-pregnanoic acid-(20)
  参考文献：
  名称：

  Behavioural observations of interactions in a free-ranging lynxLynx lynx family at kills

  摘要：

  The behaviour of a free-ranging female lynx Lynx lynx Linnaeus, 1758 and her kittens at 12 different kills was studied for 44 hours of observation from September 1996 to March 1997. The development of interactions at kills of a lynx family group showed the following pattern: until the end of September we often observed two lynx, usually both kittens, food from the kill at the same time. After the age of four months aggression between kittens was observed frequently, with the bigger kitten being dominant. From September the kittens were never again seen feeding together at the kill, However, we never observed fighting, and aggressive behaviour did not increase with the age of the, kittens. Whereas until December one of the kittens was always first at the kill, from January onwards it was mostly the adult female who ate first. She introduced her kittens to the home range of a neighbouring female where the family break-up occurred. The kittens were last seen together with their mother on 26 March. Dispersal seemed to be initiated by the female abandoning the kittens.

  DOI：

  10.1007/bf03192451

文献信息

• Über Bestandteile der Nebennierenrinde und verwandte Stoffe. (74. Mitteilung). Konfiguration der Cortico-Steroide)
  作者：J. von Euw、T. Reichstein

  DOI：10.1002/hlca.19470300124

  日期：1947.2.1