bis(cholest-5-en)-3β-yl oxalate | 7441-70-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: bis(cholest-5-en)-3β-yl oxalate
• 英文别名: dicholesteryl oxalate；Oxalsaeure-dicholesterylester；Dicholesteryl-oxalat；Bis--oxalat
• CAS: 7441-70-5
• 化学式: C₅₆H₉₀O₄
• 分子量: 827.328
• InChiKey: UREOWQGZWFSYTO-GKEYGFLISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.89
• 重原子数：
  60.0
• 可旋转键数：
  12.0
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  52.6
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  bis(cholest-5-en)-3β-yl oxalate 在 溴 作用下， 以 氯仿 为溶剂， 生成 Bis-<5α,6β-dibrom-cholestanyl-(3β)>-oxalat
  参考文献：
  名称：

  Maas,S.P.J. et al., Bulletin des Societes Chimiques Belges, 1963, vol. 72, p. 239 - 254

  摘要：

  DOI：
• 作为产物：
  描述：

  Oxalsaeure-methylester-cholesterylester 在 calcium(II) nitrate 、 calcium acetate 、 三乙胺 作用下， 以 丙酮 为溶剂， 生成 bis(cholest-5-en)-3β-yl oxalate
  参考文献：
  名称：

  Bestimmung und Isolierung von schwer acylierbaren Alkoholen mittles Methoxalsäure-anhydrid

  摘要：

  DOI：

  10.1007/bf00905487

文献信息

• Facile synthesis of new oxalate dimers of naturally occurring 3-hydroxysteroids
  作者：L. Nahar、S. D. Sarker、A. B. Turner

  DOI：10.1007/s10600-006-0211-6

  日期：2006.9

  Several symmetrical steroidal oxalate dimers were synthesised from naturally occurring 3-hydroxysteroids, namely, estrone (1), DHEA (3), pregnenolone (5), cholesterol (7), 5D-cholestane (9), and stigmasterol (11), using oxalyl chloride. Full spectroscopic data for all the new compounds are presented.

  几种对称的甾体草酸二聚体由天然存在的 3-羟基类固醇合成，即雌酮 (1)、DHEA (3)、孕烯醇酮 (5)、胆固醇 (7)、5D-胆甾烷 (9) 和豆甾醇 (11)，使用草酰氯。提供了所有新化合物的完整光谱数据。
• Effects of Spelling Errors on the Perception of Writers
  作者：David S. Kreiner、Summer D. Schnakenberg、Angela G. Green、Michael J. Costello、Anis F. McClin

  DOI：10.1080/00221300209602029

  日期：2002.1

  The authors investigated the perceived relationship between spelling errors and cognitive abilities in a series of 3 experiments, Specifically, they examined whether college students' ratings of an author's intellectual ability, logical ability, and writing ability were affected by the presence of spelling errors. In the 1st experiment, the presence of 4 spelling errors in a short essay did not significantly affect the ratings. The spelling ability of college students, as measured by a standard oral dictation spelling test, was moderately correlated with a brief test of intelligence. In a 2nd experiment, college students rated the author of a short essay as having lower ability when there was a large number of spelling errors. The effect was more pronounced on the ratings of writing ability than it was on the ratings of logical ability or intellectual ability. This finding was replicated in a 3rd experiment, in which the essay contained misspellings actually made by writers. The results suggest that spelling errors can affect how people perceive writers, particularly when there are many spelling errors. College students appear to attribute spelling errors more to writing ability than they do to general cognitive abilities such as intelligence and logical ability.
• Page; Rudy, Biochemische Zeitschrift, 1930, vol. 220, p. 304,308, 321
  作者：Page、Rudy

  DOI：——

  日期：——
• Cataline et al., Journal of the American Pharmaceutical Association (1912), 1944, vol. 33, p. 107
  作者：Cataline et al.

  DOI：——

  日期：——
• Transesterification. II. Esters of Strong Organic Acids
  作者：Alfred R. Bader、Henry A. Vogel

  DOI：10.1021/ja01136a006

  日期：1952.8