2-dimethylamino-4,5-dicarbisopropoxy-1,3,2-dioxaphospholane | 135607-89-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧戊环
• 英文名称: 2-dimethylamino-4,5-dicarbisopropoxy-1,3,2-dioxaphospholane
• 英文别名: (S,S)-2-dimethylamino-4,5-bis-(i-propoxycarbonyl)-1,3,2-dioxaphospholane
• CAS: 135607-89-5
• 化学式: C₁₂H₂₂NO₆P
• 分子量: 307.284
• InChiKey: QTDCELKGVUCWBN-UWVGGRQHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.46
• 重原子数：
  20.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  74.3
• 氢给体数：
  0.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  di(rhodium)tetracarbonyl dichloride 、 2-dimethylamino-4,5-dicarbisopropoxy-1,3,2-dioxaphospholane 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Enantioselective metal complex catalysis. 6. Rhodium catalysts for asymmetric hydrosilylation based on chiral phosphites

  摘要：

  A study has been made of the asymmetric hydrosilylation of acetophenone by diphenylsilane under the influence of rhodium complexes with chiral phosphites. The enantioselective nature of the reaction depends on the phosphite structure, the acetophenone/rhodium and ligand/rhodium ratios, and the temperature. The maximum optical yield (24%) is attained on the complex [Rh(COD)Cl]2/(S, S)-2-ethoxy-4,5-dicarbisopropoxy-1,3-2-dioxophospholane.

  DOI：

  10.1007/bf00961341
• 作为产物：
  描述：

  二甲基氯化磷胺 、 D-(-)-酒石酸二异丙酯 在 三乙胺 作用下， 以 苯 为溶剂， 反应 12.0h， 以67%的产率得到2-dimethylamino-4,5-dicarbisopropoxy-1,3,2-dioxaphospholane
  参考文献：
  名称：

  Enantioselective metal complex catalysis. 6. Rhodium catalysts for asymmetric hydrosilylation based on chiral phosphites

  摘要：

  A study has been made of the asymmetric hydrosilylation of acetophenone by diphenylsilane under the influence of rhodium complexes with chiral phosphites. The enantioselective nature of the reaction depends on the phosphite structure, the acetophenone/rhodium and ligand/rhodium ratios, and the temperature. The maximum optical yield (24%) is attained on the complex [Rh(COD)Cl]2/(S, S)-2-ethoxy-4,5-dicarbisopropoxy-1,3-2-dioxophospholane.

  DOI：

  10.1007/bf00961341