N,N'-diethyl-N,N'-di(p-tolyl)pyridine-2,6-dicarboxamide | 920282-21-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-diethyl-N,N'-di(p-tolyl)pyridine-2,6-dicarboxamide
• 英文别名: N,N′-diethyl-N,N′-di(para)tolyldipicolinamide；N,N'-Bis(p-tolyl)-N,N'-diethylpyridine-2,6-dicarboxamide；2-N,6-N-diethyl-2-N,6-N-bis(4-methylphenyl)pyridine-2,6-dicarboxamide
• CAS: 920282-21-9
• 化学式: C₂₅H₂₇N₃O₂
• 分子量: 401.508
• InChiKey: UKONYWHRXCJZJA-UHFFFAOYSA-N

物化性质

• 熔点：
  99 °C(Solv: benzene (71-43-2); chloroform (67-66-3))
• 沸点：
  599.6±50.0 °C(Predicted)
• 密度：
  1.170±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  53.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N,N'-diethyl-N,N'-di(p-tolyl)pyridine-2,6-dicarboxamide 、 uranyl nirate hexahydrate 、 1-丁基-3-甲基咪唑二(三氟甲基磺酰)酰亚胺 以 水 为溶剂， 生成 bis(N,N′-diethyl-N,N′-di(para)tolyldipicolinamide)dioxouranium(VI)(VI) perchlorate
  参考文献：
  名称：

  New Insight of Coordination and Extraction of Uranium(VI) with N-Donating Ligands in Room Temperature Ionic Liquids: N,N′-Diethyl-N,N′-ditolyldipicolinamide as a Case Study

  摘要：

  Room temperature ionic liquids (RTILs) represent a recent new class of solvents applied in liquid/liquid extraction based nuclear fuel reprocessing, whereas the related coordination chemistry and detailed extraction processes are still not well understood and remain of deep fundamental interest. The work herein provides a new insight of coordination and extraction of uranium(VI) with N-donating ligands, e.g., N,N'-diethyl-N,N'-ditolyldipicolinamide (Et(p)TDPA), in commonly used RTILs. Exploration of the extraction mechanism, speciation analyses of the extracted U(VI), and crystallographic studies of the interactions of Et(p)TDPA with U(VI) were performed, including the first structurally characterized UO2(Et(p)TDPA)2(NTf2) and UO2(Et(p)TDPA)2(PF6)2 compounds and a first case of crystallographic differentiation between the extracted U(VI) complexes in RTILs and in molecular solvents. It was found that in RTILs two Et(p)TDPA molecules coordinate with one U(VI) ion through the carbonyl and pyridine nitrogen moieties, while NTf2 and PF6 act as counterions. The absence of NO3 in the complexes is coincident with a cation-exchange extraction. In contrast, both the extracted species and extraction mechanisms are greatly different in dichloromethane, in which UO22+ coordinates in a neutral complex form with one Et(p)TDPA molecule and two NO3 cations. In addition, the complex formation in RTILs is independent of the cation exchange since incorporating UO2(NO3)(2), Et(p)TDPA, and LiNTf2 or KPF6 in a solution also produces the same complex as that in RTILs, revealing the important roles of weakly coordinating anions on the coordination chemistry between U(VI) and Et(p)TDPA. These findings suggest that cation-exchange extraction mode for ILs-based extraction system probably originates from the supply of weakly coordinating anions from RTILs. Thus the coordination of uranium(VI) with extractants as well as the cation-exchange extraction mode may be potentially changed by varying the counterions of uranyl or introducing extra anions.

  DOI：

  10.1021/ic502890w
• 作为产物：
  描述：

  2,6-氯甲酰吡啶 、 N-乙基对甲苯胺 以 氯仿 为溶剂， 反应 2.0h， 生成 N,N'-diethyl-N,N'-di(p-tolyl)pyridine-2,6-dicarboxamide
  参考文献：
  名称：

  New Insight of Coordination and Extraction of Uranium(VI) with N-Donating Ligands in Room Temperature Ionic Liquids: N,N′-Diethyl-N,N′-ditolyldipicolinamide as a Case Study

  摘要：

  Room temperature ionic liquids (RTILs) represent a recent new class of solvents applied in liquid/liquid extraction based nuclear fuel reprocessing, whereas the related coordination chemistry and detailed extraction processes are still not well understood and remain of deep fundamental interest. The work herein provides a new insight of coordination and extraction of uranium(VI) with N-donating ligands, e.g., N,N'-diethyl-N,N'-ditolyldipicolinamide (Et(p)TDPA), in commonly used RTILs. Exploration of the extraction mechanism, speciation analyses of the extracted U(VI), and crystallographic studies of the interactions of Et(p)TDPA with U(VI) were performed, including the first structurally characterized UO2(Et(p)TDPA)2(NTf2) and UO2(Et(p)TDPA)2(PF6)2 compounds and a first case of crystallographic differentiation between the extracted U(VI) complexes in RTILs and in molecular solvents. It was found that in RTILs two Et(p)TDPA molecules coordinate with one U(VI) ion through the carbonyl and pyridine nitrogen moieties, while NTf2 and PF6 act as counterions. The absence of NO3 in the complexes is coincident with a cation-exchange extraction. In contrast, both the extracted species and extraction mechanisms are greatly different in dichloromethane, in which UO22+ coordinates in a neutral complex form with one Et(p)TDPA molecule and two NO3 cations. In addition, the complex formation in RTILs is independent of the cation exchange since incorporating UO2(NO3)(2), Et(p)TDPA, and LiNTf2 or KPF6 in a solution also produces the same complex as that in RTILs, revealing the important roles of weakly coordinating anions on the coordination chemistry between U(VI) and Et(p)TDPA. These findings suggest that cation-exchange extraction mode for ILs-based extraction system probably originates from the supply of weakly coordinating anions from RTILs. Thus the coordination of uranium(VI) with extractants as well as the cation-exchange extraction mode may be potentially changed by varying the counterions of uranyl or introducing extra anions.

  DOI：

  10.1021/ic502890w

文献信息

• [EN] MULTISENSOR AND METHOD FOR EVALUATING TASTE CHARACTERISTICS OF ANALYTES<br/>[FR] DÉTECTEUR MULTIPLE ET PROCÉDÉ POUR ÉVALUER LES CARACTÉRISTIQUES GUSTATIVES DE SUBSTANCES À ANALYSER
  申请人：LEGIN ANDREY VLADIMIROVICH

  公开号：WO2012121618A1

  公开（公告）日：2012-09-13

  The present invention relates to a multisensor for evaluating taste characteristics of an analyte and a method for carrying out the same which can be employed, for example, in pharmaceutical industry, food industry, waste environmental control and other fields where such evaluation may be necessary or desirable. In particular, the present invention relates to a multisensor equipped with several chemical sensors exhibiting cross-sensitivity to components of a sample under evaluation for quantitative and qualitative assessment of some basic taste properties such as bitterness, saltiness, sweetness, sourness or umami or any combination thereof as well as some specific tastes well known in organoleptic gustatory analysis.