1,5-diphenyl-1,5-diazapentadiene | 69894-15-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,5-diphenyl-1,5-diazapentadiene
• CAS: 69894-15-1
• 化学式: C₁₅H₁₄N₂
• 分子量: 222.29
• InChiKey: ZFYNTCNECVPHDZ-NNLXQCSXSA-N

物化性质

• 沸点：
  361.9±38.0 °C(Predicted)
• 密度：
  0.98±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.01
• 重原子数：
  17.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  24.39
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  1,5-diphenyl-1,5-diazapentadiene 650.0 ℃ 、1.4 Pa 条件下， 反应 0.33h， 以89%的产率得到喹啉
  参考文献：
  名称：

  闪蒸真空热解（FVP）实验中变量影响的实证研究。

  摘要：

  对典型的闪蒸热解（FVP）实验中实验参数变化对前体向产物转化的影响进行了实验研究。温度转换图可用于优化FVP条件，并举例说明其机械意义。在给定温度下，可以通过增加背景压力或通过在炉管的一部分中填充惰性材料（特别是放置在炉管的捕集端时）或通过使用催化剂来提高转化率。尽管普遍认为FVP仅发生分子内反应，但“双重FVP”交叉实验表明，在标准条件下，在冷阱之前，气相中发生了苄基的二聚化。但是，吞吐率降低，

  DOI：

  10.1039/b410786c

文献信息

• Water soluble fluorescent compounds
  申请人：Reddington Mark

  公开号：US20070021621A1

  公开（公告）日：2007-01-25

  The invention provides a novel class of fluorescent compounds. Also provided are conjugates of the fluorescent compounds, methods of using the fluorescent compounds and their conjugates as well as kits including the fluorescent compounds and their conjugates.

  这项发明提供了一类新型荧光化合物。还提供了荧光化合物的共轭物，使用荧光化合物及其共轭物的方法，以及包括荧光化合物及其共轭物的试剂盒。
• Loaded latex optical molecular imaging probes
  申请人：Leon Jeffrey W.

  公开号：US20080181965A1

  公开（公告）日：2008-07-31

  The present invention relates to a loaded latex particle comprising a latex material made from a mixture represented by formula (X)m-(Y)n-(Z)o-(W)p, wherein Y is at least one monomer with at least two ethylenically unsaturated chemical functionalities; Z is at least one polyethylene glycol macromonomer with an average molecular weight of between 300 and 10,000; W is an ethylenic monomer different from X, Y, or Z; and X is at least one water insoluble, alkoxethyl containing monomer; and m, n, o, and p are the respective weight percentages of each monomer. The particle may be loaded with a fluorescent dye.

  本发明涉及一种载荷乳胶颗粒，该乳胶材料由以下式表示的混合物制成：(X)m-(Y)n-(Z)o-(W)p，其中Y至少是一种具有至少两个乙烯不饱和化学官能团的单体；Z至少是一种聚乙二醇马克蒙单体，其平均分子量在300至10,000之间；W是与X、Y或Z不同的乙烯单体；X至少是一种水不溶性、含有烷氧基乙烯的单体；m、n、o和p分别是每种单体的重量百分比。该颗粒可以装载荧光染料。
• CYANINE DERIVATIVES, FLUORESCENT CONJUGATES CONTAINING SAME AND USE THEREOF
  申请人：Bazin Herve

  公开号：US20100143960A1

  公开（公告）日：2010-06-10

  A subject matter of the invention is cyanine derivatives of formula: in which the dotted lines represent the atoms necessary for the formation of one or two fused aromatic rings, each ring comprising 5 or 6 carbon atoms; R 1 , R 2 , R 3 and R 4 represent, independently of one another: H; substituted or unsubstituted C 1 -C 15 alkyl; C 1 -C 6 alkoxy; (C 2 -C 12 )dialkylamino; C 1 -C 6 alkoxycarbonyl; di(C 2 -C 12 )alkylamido; a substituted or unsubstituted aryl, arylalkyl or aryloxy group; a halogen atom; a nitro; an L1-W, L2-M, L2-A or L2-G group; R 5 and R 6 represent, independently of one another: substituted or unsubstituted C 1 -C 15 alkyl; a substituted or unsubstituted aryl or arylalkyl group; an L1-W, L2-M, L2-A or L2-G group; X is chosen from: O, S or CR 7 R 8 ; Y is chosen from: O, S or CR 9 R 10 ; R 7 , R 8 , R 9 and R 10 independently represent: substituted or unsubstituted C 1 -C 15 alkyl; substituted or unsubstituted aryl, arylalkyl or aryloxy; an L1-W, L2-M, L2-A or L2-G group; R 7 and R 8 and/or R 9 and R 10 can also together form a ring comprising 5 or 6 atoms or a heterocycle comprising 4 to 5 carbon atoms and an oxygen atom; B represents a polymethine bridge comprising 1 to 5 methine groups, said groups being in particular individually unsubstituted or substituted by a substituted or unsubstituted C 1 -C 15 alkyl; a substituted or unsubstituted aryl, arylalkyl or aryloxy group; a nitro group; an L1-W, L2-M, L2-A or L2-G group; L1 and L2 are connecting arms; G is a reactive group; A is a coupling agent; M is a conjugated molecule, W is a phosphate or phosphonate ester (preferably diester), with the proviso that the cyanine derivative comprises at least one L1-W group and at least one L2-A, L2-G or L2-M group.

  本发明的主题是公式的青霉烷衍生物： 其中虚线代表形成一个或两个融合芳香环所需的原子，每个环包含5或6个碳原子；R1、R2、R3和R4独立地表示：H；取代或未取代的C1-C15烷基；C1-C6烷氧基；（C2-C12）二烷基胺；C1-C6烷氧羰基；二（C2-C12）烷基酰胺；取代或未取代的芳基、芳基烷基或芳氧基；卤素原子；硝基；L1-W、L2-M、L2-A或L2-G基团；R5和R6独立地表示：取代或未取代的C1-C15烷基；取代或未取代的芳基或芳基烷基；L1-W、L2-M、L2-A或L2-G基团；X选择自：O、S或CR7R8；Y选择自：O、S或CR9R10；R7、R8、R9和R10独立地表示：取代或未取代的C1-C15烷基；取代或未取代的芳基、芳基烷基或芳氧基；L1-W、L2-M、L2-A或L2-G基团；R7和R8和/或R9和R10还可以共同形成包含5或6个原子的环或包含4到5个碳原子和一个氧原子的杂环；B表示包含1到5个甲烷基的聚甲烷桥，所述的基团特别是单独未取代或取代的C1-C15烷基；取代或未取代的芳基、芳基烷基或芳氧基；硝基；L1-W、L2-M、L2-A或L2-G基团；L1和L2是连接臂；G是反应基团；A是偶联剂；M是共轭分子，W是磷酸酯或膦酸酯（优选为二酯），但青霉烷衍生物至少包括一个L1-W基团和至少一个L2-A、L2-G或L2-M基团。
• CYANINE DYES
  申请人：Pacific Biosciences of California, Inc.

  公开号：US20150072894A1

  公开（公告）日：2015-03-12

  The invention provides a novel class of cyanine dyes that are functionalized with sulfonic acid groups and a linker moiety that facilitates their conjugation to other species and substituent groups which increase the water-solubility, and optimize the optical properties of the dyes. Also provided are conjugates of the dyes, methods of using the dyes and their conjugates and kits including the dyes and their conjugates.

  本发明提供了一种新型的靛绿染料，其功能化为磺酸基团和连接基团，可促进其与其他物种和取代基团的共轭，并增加水溶性和优化染料的光学性质。同时，还提供了染料的共轭物、使用染料及其共轭物的方法以及包括染料及其共轭物的试剂盒。
• Functionalized Cyanine Dyes (PEG)
  申请人：Pacific Biosciences of California, Inc.

  公开号：US20150344950A1

  公开（公告）日：2015-12-03

  The invention provides a novel class of cyanine dyes that are functionalized with a linker moiety that facilitates their conjugation to other species and substituent groups which increase the water-solubility, and optimize the optical properties of the dyes. Also provided are conjugates of the dyes, methods of using the dyes and their conjugates and kits including the dyes and their conjugates.

  本发明提供了一类新型的靛烷染料，其功能化了连接基团，便于其与其他物种和取代基团结合，并增加了水溶性和优化了染料的光学性能。同时提供了该染料的共轭物、使用该染料及其共轭物的方法以及包括该染料及其共轭物的试剂盒。