4-二苯甲基-2-苯基-喹唑啉 | 103035-69-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-二苯甲基-2-苯基-喹唑啉
• 英文名称: 4-benzhydryl-2-phenyl-quinazoline
• 英文别名: 4-Benzhydryl-2-phenyl-chinazolin；4-Benzhydryl-2-phenylquinazoline
• CAS: 103035-69-4
• 化学式: C₂₇H₂₀N₂
• 分子量: 372.469
• InChiKey: OWHWMJCYGPWIHQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  二苯基乙酰氯 在 三乙胺 作用下， 生成 4-二苯甲基-2-苯基-喹唑啉
  参考文献：
  名称：

  Tandem [4+2] cycloaddition versus electrocyclisation reactions of 1-aryl-2-phenyl-5-alkyl/aryl-1,3-diazapenta-1,3,4-trienes in aza-Wittig reactions of N′-aryl-N-(triphenylphosphoranlidene) benzenecarboximidamides with ketenes

  摘要：

  1-Aryl-2-phenyl-5-alkyl/aryl-1,3-diazapenta-1,3,4-triene 3 generated in situ aza-Wittig reactions of N'-aryl-N-(triphenylphosphoranylidene)carboximidamides 1 which are shown to undergo selective [4+2] cycloaddition and electrocyclisation reactions leading to the formation of novel pyrimidinone derivatives 5 and quinazoline derivatives 7 with monosubstituted ketenes and diphenylketene, respectively. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)00119-8

文献信息

• Meerwein et al., Chemische Berichte, 1956, vol. 89, p. 224,234
  作者：Meerwein et al.

  DOI：——

  日期：——
• Tandem [4+2] cycloaddition versus electrocyclisation reactions of 1-aryl-2-phenyl-5-alkyl/aryl-1,3-diazapenta-1,3,4-trienes in aza-Wittig reactions of N′-aryl-N-(triphenylphosphoranlidene) benzenecarboximidamides with ketenes
  作者：S Jayakumar、Vipan Kumar、Mohinder P Mahajan

  DOI：10.1016/s0040-4039(01)00119-8

  日期：2001.3

  1-Aryl-2-phenyl-5-alkyl/aryl-1,3-diazapenta-1,3,4-triene 3 generated in situ aza-Wittig reactions of N'-aryl-N-(triphenylphosphoranylidene)carboximidamides 1 which are shown to undergo selective [4+2] cycloaddition and electrocyclisation reactions leading to the formation of novel pyrimidinone derivatives 5 and quinazoline derivatives 7 with monosubstituted ketenes and diphenylketene, respectively. (C) 2001 Elsevier Science Ltd. All rights reserved.