2-azacycloheptadecanone | 111412-17-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酰胺类
• 英文名称: 2-azacycloheptadecanone
• 英文别名: azacycloheptadecan-2-one；Azacycloheptadecan-2-on；Aza-2-cycloheptadecanone
• CAS: 111412-17-0
• 化学式: C₁₆H₃₁NO
• 分子量: 253.428
• InChiKey: TVJPDXTZUDNPKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-azacycloheptadecanone 在 盐酸 作用下， 以 乙醇 、 水 为溶剂， 反应 20.0h， 生成 16-aminohexadecanoic acid
  参考文献：
  名称：

  Dansyl-labeled anionic amphiphile with a hexadecanoic carbon chain: Synthesis and detection for shape transitions in organized molecular assemblies

  摘要：

  The probing properties of a new fluorophore-labeled anionic surfactant, sodium 16-(N-dansyl)aminocetylate (16-DAN-ACA) were investigated systematically in molecular assemblies, especially in the transitions between micelles and vesicles. 16-DAN-ACA can efficiently differentiate the two different aggregate types in mixed cationic and anionic surfactant systems. The fluorescence anisotropy of 16-DAN-ACA was found to be sensitive for directly detecting the micellar growth in micelles containing oppositely charged surfactants; both cationic cetyltrimethylammonium bromide (CTAB) systems and anionic sodium dodecyl sulfate (SDS) systems were studied. The results indicated that the 16-DAN-ACA is a good fluorescent probe for differentiating the different aggregates, and even more can be used to detect the micellar growth. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2014.11.113
• 作为产物：
  描述：

  cyclohexadecanone oxime 在 吡啶 、 potassium carbonate 作用下， 以 四氢呋喃 、 二氯甲烷 、 水 为溶剂， 生成 2-azacycloheptadecanone
  参考文献：
  名称：

  Dansyl-labeled anionic amphiphile with a hexadecanoic carbon chain: Synthesis and detection for shape transitions in organized molecular assemblies

  摘要：

  The probing properties of a new fluorophore-labeled anionic surfactant, sodium 16-(N-dansyl)aminocetylate (16-DAN-ACA) were investigated systematically in molecular assemblies, especially in the transitions between micelles and vesicles. 16-DAN-ACA can efficiently differentiate the two different aggregate types in mixed cationic and anionic surfactant systems. The fluorescence anisotropy of 16-DAN-ACA was found to be sensitive for directly detecting the micellar growth in micelles containing oppositely charged surfactants; both cationic cetyltrimethylammonium bromide (CTAB) systems and anionic sodium dodecyl sulfate (SDS) systems were studied. The results indicated that the 16-DAN-ACA is a good fluorescent probe for differentiating the different aggregates, and even more can be used to detect the micellar growth. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2014.11.113

文献信息

• Blends of poly(etherimides) and polyamides
  申请人：AMOCO CORPORATION

  公开号：EP0104659A2

  公开（公告）日：1984-04-04

  Described herein are compositions suitable for molding comprising a blend of poly(etherimide) polymer and a crystalline polyamide polymer. Also described herein is a poly(etherimide)-polylactam block copolymer.

  本文描述的是适合模塑的组合物，包括聚（醚酰亚胺）聚合物和结晶聚酰胺聚合物的混合物。本文还描述了一种聚（醚酰亚胺）-聚内酰胺嵌段共聚物。
• Process for preparing poly(etherimide)-polylactam block copolymers
  申请人：AMOCO CORPORATION

  公开号：EP0237849A2

  公开（公告）日：1987-09-23

  Described herein are poly(etherimide)-polylactam block copolymers, a process for their production and composi­tions suitable for molding which comprise said block co­polymers and other components such as thermoplastic poly­mers, reinforcing fibers and/or mineral fillers.

  本文描述的是聚（醚酰亚胺）-聚内酰胺嵌段共聚物、其生产工艺和适用于模塑的组合物，这些组合物由上述嵌段共聚物和其他成分（如热塑性聚合物、增强纤维和/或矿物填料）组成。
• Syntactic foam plugs
  申请人：——

  公开号：US20020149138A1

  公开（公告）日：2002-10-17

  The present invention provides an improved syntactic foam plug for plug assist thermoforming wherein such plug is composed of a thermoplastic material having a relatively high melting and/or glass transition temperature. Accordingly, the subject invention encompasses diminishing or removing the undesirable characteristics of thermoset syntactic plugs while increasing the ease by which these articles may be constructed for a given use, by forming such plugs from syntactic foams containing thermoplastics.

  本发明提供了一种用于塞子辅助热成型的改进型合成泡沫塑料塞子，其中这种塞子由具有相对较高熔化温度和/或玻璃化温度的热塑性材料组成。因此，本发明包括减少或消除热固性合成泡沫塑料塞子的不良特性，同时通过用含有热塑性塑料的合成泡沫塑料形成这种塞子，使这些物品更容易制造，以满足特定用途。
• [EN] MEDICAMENTS CONTAINING AZACYCLODIPHOSPHONIC ACID DERIVATIVES, NOVEL AZACYCLODIPHOSPHONIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THEM
  申请人：BOEHRINGER MANNHEIM GMBH

  公开号：WO1992019628A1

  公开（公告）日：1992-11-12

  (DE) Arzneimittel zur Behandlung von Knochenstoffwechselstörungen, enthaltend mindestens eine Verbindung der Formel (I), in der n eine ganze Zahl zwischen 7 und 16 und R Wasserstoff oder C1-C4-Alkyl bedeuten, sowie deren pharmakologisch unbedenkliche Salze und neue Azacycloalkan-2,2-diphosphonsäure-Derivate.(EN) Medicaments for the treatment of bone metabolism disorders containing at least one compound of formula (I) in which n is a whole number between 7 and 16 and R is hydrogen or C1-C4-alkyl, and their pharmacologically acceptable salts and novel azacycloalkane-2,2-diphosphonic acid derivatives.(FR) Médicaments pour le traitement de troubles du métabolisme osseux, renfermant au moins un composé de formule (I) dans laquelle n est un nombre entier compris entre 7 et 16, et R désigne un hydrogène ou un alkyle en C1-C4, ainsi que leurs sels pharmacologiquement acceptables, et nouveaux dérivés de l'acide azacycloalcane-2,2-diphosphonique.

  (德) 用于治疗骨代谢紊乱的药物，包含至少一种式(I)的化合物，其中n是7到16之间的整数，R是氢或C1-C4烷基，以及其药理学上可接受的盐和新的氮杂环烷基-2,2-二磷酸基酸衍生物。 (英) 用于治疗骨代谢紊乱的药物，包含至少一种式(I)的化合物，其中n是7到16之间的整数，R是氢或C1-C4烷基，以及其药理学上可接受的盐和新的氮杂环烷基-2,2-二磷酸基酸衍生物。 (法) 用于治疗骨代谢紊乱的药物，包含至少一种式(I)的化合物，其中n是7到16之间的整数，R是氢或C1-C4烷基，以及其药理学上可接受的盐和新的氮杂环烷基-2,2-二磷酸基酸衍生物。
• Ruzicka et al., Helvetica Chimica Acta, 1949, vol. 32, p. 552
  作者：Ruzicka et al.

  DOI：——

  日期：——