4-叔丁基-1-(3-磺丙基)吡啶氢氧化内盐水合物 | 570412-84-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 4-叔丁基-1-(3-磺丙基)吡啶氢氧化内盐水合物
• 英文名称: 3-(4-(tert-butyl)pyridinio)-1-propanesulfonate
• 英文别名: 3-(4-Tert-butylpyridin-1-ium-1-yl)propane-1-sulfonate
• CAS: 570412-84-9
• 化学式: C₁₂H₁₉NO₃S
• 分子量: 257.354
• InChiKey: QMGYGZCGWOKPGR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  69.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  phosphotungstic acid 、 4-叔丁基-1-(3-磺丙基)吡啶氢氧化内盐水合物 以 水 为溶剂， 反应 72.0h， 生成
  参考文献：
  名称：

  Organic–inorganic polyoxometalate based salts as thermoregulated phase-separable catalysts for selective oxidation of thioethers and thiophenes and deep desulfurization of model fuels

  摘要：

  Synthesis of various organic-inorganic polyoxometalate based salts composed of sulfonated pyridinum cations and the Keggin tungstophosphate anion (PW12O403-) and their subsequent application in the oxidation of methyl phenyl sulfide with hydrogen peroxide in aqueous media was reported. Special attention was paid to the temperature-dependent solubility of the salts as a function of the organic cation in water. Cyclic voltammetry was further used for the investigation of the redox behavior of these catalysts. Based on these properties, a novel thermoregulated phase-separable catalyst was introduced and successfully used for the selective oxidation of thioethers and thiophenes to the corresponding sulfoxides or sulfones. Catalytic oxidation of the sulfur-containing model oil (methyl phenyl sulfide, dibenzothiophene and thiophene) was also studied under optimized conditions. In both cases, excellent conversion and selectivity were obtained in relatively short reaction times. This novel catalyst showed the characteristic of homogeneous reaction at ambient temperatures and phase-separation at lower temperatures. By simple decantation, the catalyst could be easily separated from the products upon cooling of the reaction mixture and could be reused several times with high recycling efficiency. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2013.09.009
• 作为产物：
  描述：

  4-叔丁基吡啶 、 1,3-丙烷磺内酯 以 甲苯 为溶剂， 反应 24.0h， 生成 4-叔丁基-1-(3-磺丙基)吡啶氢氧化内盐水合物
  参考文献：
  名称：

  Organic–inorganic polyoxometalate based salts as thermoregulated phase-separable catalysts for selective oxidation of thioethers and thiophenes and deep desulfurization of model fuels

  摘要：

  Synthesis of various organic-inorganic polyoxometalate based salts composed of sulfonated pyridinum cations and the Keggin tungstophosphate anion (PW12O403-) and their subsequent application in the oxidation of methyl phenyl sulfide with hydrogen peroxide in aqueous media was reported. Special attention was paid to the temperature-dependent solubility of the salts as a function of the organic cation in water. Cyclic voltammetry was further used for the investigation of the redox behavior of these catalysts. Based on these properties, a novel thermoregulated phase-separable catalyst was introduced and successfully used for the selective oxidation of thioethers and thiophenes to the corresponding sulfoxides or sulfones. Catalytic oxidation of the sulfur-containing model oil (methyl phenyl sulfide, dibenzothiophene and thiophene) was also studied under optimized conditions. In both cases, excellent conversion and selectivity were obtained in relatively short reaction times. This novel catalyst showed the characteristic of homogeneous reaction at ambient temperatures and phase-separation at lower temperatures. By simple decantation, the catalyst could be easily separated from the products upon cooling of the reaction mixture and could be reused several times with high recycling efficiency. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2013.09.009

文献信息

• [EN] PROCESS FOR SELECTIVE ETHYLENE OLIGOMERIZATION WITH ANTIFOULING COMPONENTS<br/>[FR] PROCÉDÉ D'OLIGOMÉRISATION SÉLECTIVE DE L'ÉTHYLÈNE AVEC DES COMPOSANTS ANTISALISSURE
  申请人：SAUDI ARABIAN OIL CO

  公开号：WO2018106764A1

  公开（公告）日：2018-06-14

  A process for selectively producing 1-butene comprises contacting at least one antifouling agent with at least one aluminum alkyl compound to form at least one antifouling compound in a first step. The antifouling compound may comprise a structure comprising a central aluminum molecule bound to an R1 group, bound to an R2 group, and bound to an R3 group. The process further comprises feeding the antifouling compound, an additional amount of the aluminum alkyl compound, at least one titanate compound, and ethylene into a reactor to dimerize ethylene in a second step. The titanate compound is fed as a stream separated from the streams of the antifouling compound and the additional amount of the aluminum alkyl compound. The molar ratio of the sum of the aluminum alkyl compound to the titanate compound is equal to or higher than 1.5 and equal to or lower than 3.0.

  一种选择性生产1-丁烯的工艺包括在第一步中将至少一种防污剂与至少一种铝烷基化合物接触，形成至少一种防污化合物。防污化合物可能包括一个结构，其中包含一个中心铝分子与一个R1基团结合，与一个R2基团结合，与一个R3基团结合。该工艺进一步包括在第二步将防污化合物、额外量的铝烷基化合物、至少一种钛酸盐化合物和乙烯送入反应器以使乙烯二聚。钛酸盐化合物作为一种流分离出来，与防污化合物和额外量的铝烷基化合物的流分开。铝烷基化合物总量与钛酸盐化合物的摩尔比等于或高于1.5且等于或低于3.0。
• [EN] ANTIFOULING OLIGOMERIZATION CATALYST SYSTEMS<br/>[FR] SYSTÈMES DE CATALYSEUR D'OLIGOMÉRISATION ANTISALISSURES
  申请人：SAUDI ARABIAN OIL CO

  公开号：WO2016205194A1

  公开（公告）日：2016-12-22

  A catalyst system that may reduce polymeric fouling may include at least one titanate compound, at least one aluminum compound, and an antifouling agent. The antifouling agent may be chosen from one or more of a phosphonium or phosphonium salt; a sulfonate or a sulfonate salt; a sulfonium or sulfonium salt; an ester including a cyclic moiety; an anhydride; a polyether; and a long-chained amine-capped compound. The catalyst system may further include a non-polymeric ether compound.

  可能减少聚合物污垢的催化剂系统可能包括至少一种钛酸盐化合物、至少一种铝化合物和一种防污剂。防污剂可以选择自磷酚或磷酚盐；磺酸盐或磺酸盐；磺鎓或磺鎓盐；包括环状基团的酯；酸酐；聚醚；和长链胺端基化合物中的一种或多种。催化剂系统还可以包括一种非聚合物醚化合物。
• Methods for depyrogenating a seaweed extract
  申请人：MARINOVA PTY LTD

  公开号：US10149874B2

  公开（公告）日：2018-12-11

  A method is provided for treating a seaweed extract having a target molecule and a pyrogenic agent. The method includes inactivating the pyrogenic agent and/or removing the pyrogenic agent. The method results in a reduction in pyrogenicity of the extract. The method is useful in the preparation of pharmaceutical compositions and biomaterials for which pyrogen removal is critical.

  提供了一种处理具有目标分子和热原剂的海藻提取物的方法。该方法包括灭活热原剂和/或去除热原剂。该方法可降低提取物的热原性。该方法适用于制备对去除热原至关重要的药物组合物和生物材料。
• Methods and compositions for inactivating enveloped viruses
  申请人：Biogen MA Inc.

  公开号：US10188732B2

  公开（公告）日：2019-01-29

  Aspects of the invention provide therapeutic recombinant protein preparations and methods of preparing therapeutic recombinant protein, which methods include contacting recombinant protein preparations with zwitterionic detergent at or above critical micelle concentration of the detergent.

  本发明的各个方面提供了治疗性重组蛋白制剂和制备治疗性重组蛋白的方法，这些方法包括在洗涤剂的临界胶束浓度或以上将重组蛋白制剂与齐聚物洗涤剂接触。
• Process for selective ethylene oligomerization with antifouling components
  申请人：Sogo Kenji

  公开号：US10280125B2

  公开（公告）日：2019-05-07

  A process for selectively producing 1-butene comprises contacting at least one antifouling agent with at least one aluminum alkyl compound to form at least one antifouling compound in a first step. The antifouling compound may comprise a structure comprising a central aluminum molecule bound to an R1 group, bound to an R2 group, and bound to an R3 group. The process further comprises feeding the antifouling compound, an additional amount of the aluminum alkyl compound, at least one titanate compound, and ethylene into a reactor to dimerize ethylene in a second step. The titanate compound is fed as a stream separated from the streams of the antifouling compound and the additional amount of the aluminum alkyl compound. The molar ratio of the sum of the aluminum alkyl compound to the titanate compound is equal to or higher than 1.5 and equal to or lower than 3.0.

  一种选择性生产 1-丁烯的工艺包括在第一步中将至少一种防污剂与至少一种铝烷基化合物接触以形成至少一种防污化合物。防污化合物可包括一种结构，该结构包括与 R1 基团结合的中心铝分子、与 R2 基团结合的中心铝分子和与 R3 基团结合的中心铝分子。该工艺还包括在第二步中将防污化合物、额外量的铝烷基化合物、至少一种钛酸酯化合物和乙烯送入反应器中使乙烯二聚。钛酸酯化合物从防污化合物和额外的铝烷基化合物流中分离出来。铝烷基化合物与钛酸酯化合物之和的摩尔比等于或高于 1.5，等于或低于 3.0。