cis-4,4'-diheptylamido-dibenzo-18-crown-6 | 1259886-95-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: cis-4,4'-diheptylamido-dibenzo-18-crown-6
• CAS: 1259886-95-7
• 化学式: C₃₄H₅₀N₂O₈
• 分子量: 614.78
• InChiKey: DFFSIVJAADKSDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.77
• 重原子数：
  44.0
• 可旋转键数：
  12.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  113.58
• 氢给体数：
  2.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  cis-4,4'-diheptylamido-dibenzo-18-crown-6 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 4.0h， 以50%的产率得到cis-4,4'-di(heptylamino)-dibenzo-18-crown-6
  参考文献：
  名称：

  Di(1H,1H,2H,2H-perfluorooctyl)-dibenzo-18-crown-6: A “light fluorous” recyclable phase transfer catalyst

  摘要：

  series of dibenzo-18-crown-6 lariat ethers containing two C(7)H(15) (11) (CH(2))(2)C(6)F(13) (14) (CH(2))(2)C(8)F(17) (15) NHC(7)H(15) (18) and NHCH(2)C(6)F(13) (19) sidearms were prepared and the single crystal X-ray structure of cis-4 4'-di(1H 1H 2H 2H-perfluorodecyl)-dibenzo-18-crown 6 (15a) is reported The light fluorous dibenzo-18-crown-6 ether (14) has emerged as a stable and robust PTC catalyst which can be recycled efficiently by fluorous solid-phase extraction and gives better PTC catalytic activity compared to the parent non-fluorinated PTC catalyst dibenzo-18-crown-6 and the alkylated derivative (11) in aliphatic and aromatic nucleophilic substitutions (C) 2010 Elsevier B V All rights reserved

  DOI：

  10.1016/j.jfluchem.2010.06.002
• 作为产物：
  描述：

  4',5''-daminodibenzo-18-crown-6 、 庚酰氯 以 丙酮 为溶剂， 反应 14.0h， 以47%的产率得到cis-4,4'-diheptylamido-dibenzo-18-crown-6
  参考文献：
  名称：

  Di(1H,1H,2H,2H-perfluorooctyl)-dibenzo-18-crown-6: A “light fluorous” recyclable phase transfer catalyst

  摘要：

  series of dibenzo-18-crown-6 lariat ethers containing two C(7)H(15) (11) (CH(2))(2)C(6)F(13) (14) (CH(2))(2)C(8)F(17) (15) NHC(7)H(15) (18) and NHCH(2)C(6)F(13) (19) sidearms were prepared and the single crystal X-ray structure of cis-4 4'-di(1H 1H 2H 2H-perfluorodecyl)-dibenzo-18-crown 6 (15a) is reported The light fluorous dibenzo-18-crown-6 ether (14) has emerged as a stable and robust PTC catalyst which can be recycled efficiently by fluorous solid-phase extraction and gives better PTC catalytic activity compared to the parent non-fluorinated PTC catalyst dibenzo-18-crown-6 and the alkylated derivative (11) in aliphatic and aromatic nucleophilic substitutions (C) 2010 Elsevier B V All rights reserved

  DOI：

  10.1016/j.jfluchem.2010.06.002