N-((5-(4-fluoro-2-(2-fluoroethoxy)phenyl)pyridin-3-yl)methyl)cyclopentanamine | 1531653-13-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-((5-(4-fluoro-2-(2-fluoroethoxy)phenyl)pyridin-3-yl)methyl)cyclopentanamine
• 英文别名: N-[[5-[4-fluoro-2-(2-fluoroethoxy)phenyl]pyridin-3-yl]methyl]cyclopentanamine
• CAS: 1531653-13-0
• 化学式: C₁₉H₂₂F₂N₂O
• 分子量: 332.393
• InChiKey: GRCYAAOWKKJUGB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  34.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] COMPOUND AND USE OF COMPOUND TO PREPARE A RADIOLABELLED COMPOUND<br/>[FR] COMPOSÉ ET UTILISATION D'UN COMPOSÉ POUR PRÉPARER UN COMPOSÉ RADIOMARQUÉ
  申请人：STICHTING VU VUMC

  公开号：WO2014007629A1

  公开（公告）日：2014-01-09

  The invention is directed to a compound according to formula (1) wherein R2 is fluorine, X is nitrogen or carbon and R3 is an organic group. The invention is also directed to the use of this compound as a precursor for the preparation of a11C or18F-radio labelled compound. The radio labelled compound may be used in an in vivo diagnostic or imaging method.

  该发明涉及一种化合物，其化学式为（1），其中R2为氟，X为氮或碳，R3为有机基团。该发明还涉及将该化合物用作制备a11C或18F标记化合物的前体的用途。这种放射性标记化合物可用于体内诊断或成像方法中。
• COMPOUND AND USE OF COMPOUND TO PREPARE A RADIOLABELLED COMPOUND
  申请人：STICHTING VU-VUMC

  公开号：US20150183743A1

  公开（公告）日：2015-07-02

  The invention is directed to a compound according to formula (1) wherein R 2 is fluorine, X is nitrogen or carbon and R 3 is an organic group. The invention is also directed to the use of this compound as a precursor for the preparation of a 11 C or 18 F-radio labelled compound. The radio labelled compound may be used in an in vivo diagnostic or imaging method.