(8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenantren-3-yl 4-(dec-9-enyloxy)benzoate | 202819-70-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenantren-3-yl 4-(dec-9-enyloxy)benzoate
• CAS: 202819-70-3
• 化学式: C₄₅H₇₀O₃
• 分子量: 659.049
• InChiKey: GHIGHIOSYVTTSI-HHSPMZPPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.94
• 重原子数：
  48.0
• 可旋转键数：
  18.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  35.53
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenantren-3-yl 4-(dec-9-enyloxy)benzoate 、 1,1,3,3-四甲基二硅氧烷 在 chloroplatinic acid 1,1,3,3-tetramethyl-1,3-divinyldisiloxane complex 作用下， 以 甲苯 、 xylene 为溶剂， 反应 2.0h， 以89%的产率得到4-[11-(1,1,3,3-Tetramethyl-disiloxanyl)-undecyloxy]-benzoic acid (3S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester
  参考文献：
  名称：

  Cholesteric Silatranes

  摘要：

  Most liquid crystals with a C-3 symmetry have so far been discotic systems, e.g., triphenylenes. In the context of calamitic systems research has concentrated on triptycenes and to a lesser extend on silatranes. In this contribution we report our investigations of cholesteric silatrane systems, which have been obtained by connecting a tribenzylsilatrane core to cholesteric groups via alkyl and siloxane spacer groups.

  DOI：

  10.1080/15421400590955118
• 作为产物：
  描述：

  11-溴-1-十一烯 在 4-二甲氨基吡啶 、 氢氧化钾 、 对甲苯磺酸 、 N,N'-二环己基碳二亚胺 、 potassium iodide 作用下， 以 乙醇 、 水 、 二甲基亚砜 为溶剂， 反应 44.0h， 生成 (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenantren-3-yl 4-(dec-9-enyloxy)benzoate
  参考文献：
  名称：

  Cholesteric Silatranes

  摘要：

  Most liquid crystals with a C-3 symmetry have so far been discotic systems, e.g., triphenylenes. In the context of calamitic systems research has concentrated on triptycenes and to a lesser extend on silatranes. In this contribution we report our investigations of cholesteric silatrane systems, which have been obtained by connecting a tribenzylsilatrane core to cholesteric groups via alkyl and siloxane spacer groups.

  DOI：

  10.1080/15421400590955118

文献信息

• Helically Twisted Chiral Arrays of Gold Nanoparticles Coated with a Cholesterol Mesogen
  作者：Liliana Cseh、Xiaobin Mang、Xiangbing Zeng、Feng Liu、Georg H. Mehl、Goran Ungar、Giuliano Siligardi

  DOI：10.1021/jacs.5b05059

  日期：2015.10.14

  Gold nanoparticles have been prepared and surface-functionalized with a 1:1 molar mixture of a hexylthiol ligand and a chiral mesogenic ligand consisting of a cholesterylbenzoate attached via an undecylthiol spacer. Grazing incidence X-ray diffraction showed that upon annealing a columnar liquid crystal (LC) structure develops with the nanoparticles forming strings on a regular oblique 2d lattice. Synchrotron radiation circular dichroism is substantially enhanced upon the isotropic LC transition. In the proposed structural model, layers of Au columns rotate by a small angle relative to their neighbors, with the columns winding around a helical axis. The work demonstrates that it is possible to obtain chiral LC superstructures from nanoparticles coated with chiral mesogen without the addition of a separate LC or chiral dopants. The results provide direction in the development of plasmonic metamaterials interacting selectively with circularly polarized light.