S-[1-(furan-2-yl)-1-oxopentan-2-yl] benzenecarbothioate | 1448459-59-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: S-[1-(furan-2-yl)-1-oxopentan-2-yl] benzenecarbothioate
• CAS: 1448459-59-3
• 化学式: C₁₆H₁₆O₃S
• 分子量: 288.367
• InChiKey: QMFGDVJVSKOGTP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  72.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  、 呋喃甲酰氯 在 copper (II)-fluoride 作用下， 以 1,4-二氧六环 为溶剂， 反应 18.0h， 以60%的产率得到S-[1-(furan-2-yl)-1-oxopentan-2-yl] benzenecarbothioate
  参考文献：
  名称：

  Copper-catalyzed cross-coupling reaction of α-sulfur-substituted alkylstannanes with acid chlorides

  摘要：

  Copper compounds were found to catalyze the cross-coupling reaction of a-sulfur-substituted alkylstannanes with acid chlorides. Under the optimized conditions (CuF2 (1 mol %), 1,4-dioxane, 102 degrees C), various substrates coupled to afford the corresponding a-sulfur-substituted ketones in good yields. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.06.088

文献信息

• Copper-catalyzed cross-coupling reaction of α-sulfur-substituted alkylstannanes with acid chlorides
  作者：Hirotaka Kagoshima、Naoshi Takahashi

  DOI：10.1016/j.tetlet.2013.06.088

  日期：2013.8

  Copper compounds were found to catalyze the cross-coupling reaction of a-sulfur-substituted alkylstannanes with acid chlorides. Under the optimized conditions (CuF2 (1 mol %), 1,4-dioxane, 102 degrees C), various substrates coupled to afford the corresponding a-sulfur-substituted ketones in good yields. (C) 2013 Elsevier Ltd. All rights reserved.