2-(4-Bromo-2-(isoxazol-5-YL)phenoxy)acetic acid | 763109-06-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(4-Bromo-2-(isoxazol-5-YL)phenoxy)acetic acid
• 英文别名: 2-[4-bromo-2-(1,2-oxazol-5-yl)phenoxy]acetic acid
• CAS: 763109-06-4
• 化学式: C₁₁H₈BrNO₄
• 分子量: 298.09
• InChiKey: AEZJDRISVAYEBX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  72.6
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS
  申请人：NMD Pharma A/S

  公开号：EP3724173B1

  公开（公告）日：2021-09-22
• Compounds For The Treatment Of Neuromuscular Disorders
  申请人：NMD PHARMA A/S

  公开号：US20190183863A1

  公开（公告）日：2019-06-20

  The present invention relates to compounds suitable for treating, ameliorating and/or preventing neuromuscular disorders, including the reversal of drug-induced neuromuscular blockade. The compounds as defined herein preferably inhibit the CIC-1 ion channel.
• [EN] COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS<br/>[FR] COMPOSÉS DESTINÉS AU TRAITEMENT DE TROUBLES NEUROMUSCULAIRES
  申请人：NMD PHARMA AS

  公开号：WO2019115781A1

  公开（公告）日：2019-06-20

  The present invention relates to compounds suitable for treating, ameliorating and/or preventing neuromuscular disorders, including the reversal of drug-induced neuromuscular blockade. The compounds as defined herein preferably inhibit the ClC-1 ion channel.