2-methoxy-4-methyl-5-(1,2,2,2-tetrachloro-ethyl)-benzoic acid | 858843-12-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-methoxy-4-methyl-5-(1,2,2,2-tetrachloro-ethyl)-benzoic acid
• 英文别名: 6-Methoxy-4-methyl-3-(α.β.β.β-tetrachlor-aethyl)-benzoesaeure；2-Methoxy-4-methyl-5-(1,2,2,2-tetrachlor-aethyl)-benzoesaeure
• CAS: 858843-12-6
• 化学式: C₁₁H₁₀Cl₄O₃
• 分子量: 332.011
• InChiKey: GNJAIMKBNVYODU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.35
• 重原子数：
  18.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  46.53
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  2-methoxy-4-methyl-5-(1,2,2,2-tetrachloro-ethyl)-benzoic acid 在 氢氧化钾 作用下， 生成 4-methyl-2-methoxy-5-trichlorovinyl-benzoic acid
  参考文献：
  名称：

  Dissociative identity disorder and the nurse-patient relationship in the acute care setting: An action research study

  摘要：

  ABSTRACT This paper presents the results of an action research study into the acute care experience of Dissociative Identity Disorder. The study, which was grounded in principles of critical social science, utilized focus group interviews and narrative construction. Nurses and patients are under‐represented in all clinical evaluation and their voices need to be heard if services are to be truly collaborative. Findings of the study extend intrapsychic theories of trauma to emphasize the interpersonal relationship between nurse and person who can work together to facilitate recovery from trauma, make connections both intra and interpersonally and build resilience.

  DOI：

  10.1046/j.1440-0979.2001.00188.x
• 作为产物：
  描述：

  2-methoxy-4-methyl-6-(2,2,2-trichloro-1-hydroxy-ethyl)-benzoic acid 在 盐酸 、 硫酸 作用下， 生成 2-methoxy-4-methyl-5-(1,2,2,2-tetrachloro-ethyl)-benzoic acid
  参考文献：
  名称：

  Dissociative identity disorder and the nurse-patient relationship in the acute care setting: An action research study

  摘要：

  ABSTRACT This paper presents the results of an action research study into the acute care experience of Dissociative Identity Disorder. The study, which was grounded in principles of critical social science, utilized focus group interviews and narrative construction. Nurses and patients are under‐represented in all clinical evaluation and their voices need to be heard if services are to be truly collaborative. Findings of the study extend intrapsychic theories of trauma to emphasize the interpersonal relationship between nurse and person who can work together to facilitate recovery from trauma, make connections both intra and interpersonally and build resilience.

  DOI：

  10.1046/j.1440-0979.2001.00188.x

文献信息

• A consumer's perspective of a suicide intervention programme
  作者：Samar Aoun、Lyn Johnson

  DOI：10.1046/j.1440-0979.2001.00199.x

  日期：2001.6

  ABSTRACT The objective of this study was to assess the impact of a suicide intervention program from a consumer perspective. Self‐administered questionnaires were distributed to consumers who had been referred to a suicide intervention counsellor in the 2‐year period of the programme in rural southwest Western Australia. Three‐quarters of respondents were positive about their experience with the service, with half of the respondents no longer having thoughts of suicide and only 20% of all respondents reporting having attempted deliberate self‐harm postcounselling. Reported suicidal ideation and attempted self‐harm were much higher in the dissatisfied group. Dissatisfaction of respondents stemmed from the history of their treatment and ‘the hassle created by the many systems for them to access care’. However, the overall outcome of this study is that, from the consumer’s perspective, a high intensity approach to suicide intervention resolved or improved the presenting problem and their ability to deal with it.