[3,5-bis(hydroxy)benzyloxy]decan-1-yl-10-thioacetate | 946124-76-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [3,5-bis(hydroxy)benzyloxy]decan-1-yl-10-thioacetate
• 英文别名: S-[10-[(3,5-dihydroxyphenyl)methoxy]decyl] ethanethioate
• CAS: 946124-76-1
• 化学式: C₁₉H₃₀O₄S
• 分子量: 354.511
• InChiKey: QGBLHFPWNQCQTP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  24
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  92.1
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  [3,5-bis(hydroxy)benzyloxy]decan-1-yl-10-thioacetate 在 氢氧化钾 、 potassium carbonate 作用下， 以 乙醇 、 丙酮 为溶剂， 反应 24.0h， 生成 [3,5-bis(1H,1H,2H,2H,3H,3H,4H,4H-perfluorodecan-1-yloxy)benzyloxy]decan-1-yl-10-thiol
  参考文献：
  名称：

  Synthesis of Supercritical Carbon Dioxide Soluble Perfluorinated Dendrons for Surface Modification

  摘要：

  The rational design, synthesis, and characterization of a series of novel perfluorinated dendrons 14a,b, 25a,b, 26a,b, and 18 are described. The dendrimers were designed to have a thiol at the focal point for attachment to a gold surface to enable the fabrication of self-assembled monolayers (SAMs). Perfluorinated tails were attached to the periphery to provide solubility in supercritical carbon dioxide, and to increase the hydrophobicity and the stability of self-assembled monolayers formed. Mitsunobu reactions were utilized to provide high-yielding steps allowing large-scale production of the novel dendrimers.

  DOI：

  10.1021/jo070293f
• 作为产物：
  描述：

  1,10-癸二醇 在 四(三苯基膦)钯 吡啶 、 N,N,N,N-tetraethylammonium tetrafluoroborate 、 potassium hydride 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 14.83h， 生成 [3,5-bis(hydroxy)benzyloxy]decan-1-yl-10-thioacetate
  参考文献：
  名称：

  Synthesis of Supercritical Carbon Dioxide Soluble Perfluorinated Dendrons for Surface Modification

  摘要：

  The rational design, synthesis, and characterization of a series of novel perfluorinated dendrons 14a,b, 25a,b, 26a,b, and 18 are described. The dendrimers were designed to have a thiol at the focal point for attachment to a gold surface to enable the fabrication of self-assembled monolayers (SAMs). Perfluorinated tails were attached to the periphery to provide solubility in supercritical carbon dioxide, and to increase the hydrophobicity and the stability of self-assembled monolayers formed. Mitsunobu reactions were utilized to provide high-yielding steps allowing large-scale production of the novel dendrimers.

  DOI：

  10.1021/jo070293f

文献信息

• Fabrication of self-assembled dendron monolayers
  申请人：Seiko Epson Corporation

  公开号：US07524998B2

  公开（公告）日：2009-04-28

  A dendron (2) comprising a focal point (4) and a plurality of fluorinated end groups (9) is disclosed, including one having a thiol, a silane, a carboxylic acid, a phosphonate or another moiety at the focal point suitable for chemisorption to a substrate (3). A self-assembled monolayer comprising a plurality of dendrons bonded to a substrate and a device comprising the self-assembled monolayer are also disclosed.

  揭示了一种包括一个焦点（4）和多个氟化末端基团（9）的树状分子（2），其中在焦点处具有硫醇、硅烷、羧酸、膦酸酯或其他适用于化学吸附到基底（3）的基团的树状分子。还揭示了一种包括多个与基底结合的树状分子的自组装单分子层，以及包括该自组装单分子层的器件。