3-chloro-2-methanesulfonyl-5-trifluoromethylpyridine | 475155-72-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-chloro-2-methanesulfonyl-5-trifluoromethylpyridine
• 英文别名: 3-chloro-2-methylsulfonyl-5-(trifluoromethyl)pyridine
• CAS: 475155-72-7
• 化学式: C₇H₅ClF₃NO₂S
• 分子量: 259.636
• InChiKey: YSSOBLKKADBBKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  55.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  3-chloro-2-methanesulfonyl-5-trifluoromethylpyridine 、 4-[3-(2-chloro-6-fluorophenyl)-5-methyl-1H-1,2,4-triazol-1-yl]phenylmethanol 在 sodium hydride 作用下， 以 DMF (N,N-dimethyl-formamide) 为溶剂， 反应 55.0h， 以46%的产率得到3-(2-chloro-6-fluorophenyl)-1-[4-(3-chloro-5-trifluoromethylpyridin-2-yloxymethyl)phenyl]-5-methyl-1H-1,2,4-triazole
  参考文献：
  名称：

  EP1386915

  摘要：

  公开号：

文献信息

• [EN] NOVEL DICHLOROPROPENE DERIVATIVES<br/>[FR] NOUVEAUX DERIVES DE DICHLOROPROPENE
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2005095330A1

  公开（公告）日：2005-10-13

  Formula (I), wherein X represents a group -O-A1- or a group -N=A2-, Y represents a single bond, O or S, or X and Y together may represent O, Q represents an aryl group that may be optionally substituted, a heterocyclic group that may be optionally substituted, or haloalkenyl, m represents 2 or 3, R1 represents halogen, n represents 0 or 1, A1 represents alkylene, alkylidene, alkenylene, cycloalkylene, alkylidenecycloalkyl, alkyleneoxyalkylene, alkyleneoxyiminoalkylidyne, alkan-yl-ylidene-iminooxyalkylene, alkan-yl-ylidene-iminooxyalkylidene or a group -(alkylene)-O(CO)NH-, A2 represents alkylidyne, provided that , X and Y together represent O, in case that Q represents haloalkenyl, and X represents a group -O-A1- and Y represents a single bond or O, in case that Q represents a heterocyclic group that may be optionally substituted.

  公式（I），其中X代表一个基团-O-A1-或一个基团-N=A2-，Y代表单键，O或S，或者X和Y在一起可以代表O，Q代表一个可能被选择性取代的芳基团，一个可能被选择性取代的杂环基团，或卤代烯基，m代表2或3，R1代表卤素，n代表0或1，A1代表烷基，烷基亚烯，烯烃基，环烷基，烷基亚烯环烷基，烷氧基烷基，烷氧基亚胺烷基亚烯，烷基亚烯亚胺氧基烷基亚烯，烷基亚烯亚胺氧基烷基亚烯或一个基团-(烷基亚烯)-O(CO)NH-，A2代表烷基亚烯，条件是，若X和Y在一起代表O，则Q代表卤代烯基，且X代表一个基团-O-A1-且Y代表单键或O，若Q代表一个可能被选择性取代的杂环基团。
• [EN] POLYHALOGENATED PROPENE BENZOQUINONE DIOXIME DERIVATIVES AND ITS USE AS PESTICIDES<br/>[FR] DERIVES DE PROPENE-BENZOQUINONE-DIOXIME POLYHALOGENES ET LEUR UTILISATION EN TANT QUE PESTICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2006037496A1

  公开（公告）日：2006-04-13

  Novel dihalogenopropene derivatives of the formula (I) and of the formula (Ia), wherein A, A1, A2, G, Q, R1, R2, R3, R4, and X have the meaning provided in the description, Methods and intermediates for their production as well as their use for combattiing pests.

  具有以下公式(I)和公式(Ia)的新型二卤代丙烯衍生物，其中A、A1、A2、G、Q、R1、R2、R3、R4和X的含义如描述中所提供的含义，以及它们的生产方法和中间体，以及它们用于对抗害虫的用途。
• Azole compounds, process for preparation of the same and use thereof
  申请人：Itoh Shigeyuki

  公开号：US20050009834A1

  公开（公告）日：2005-01-13

  The invention provides novel azole compounds useful as pest controllers and novel pest controllers containing the compounds as the active ingredient. The invention discloses azole compounds represented by the following general formula, a production process for preparation of the compounds, and use thereof as insecticides or acaricides: wherein X 1 to X 5 and Z 1 to Z 4 are each N, C—H, C-halogen, C-alkyl, or the like; Y 1 and Y 2 are each N or CH, with the proviso that both Y 1 and Y 2 must not be CH; A is a single bond, O, or the like; Ar is an optionally substituted aromatic residue; B is halogeno, alkyl, or the like; R 1 is H, halogeno, alkyl, or the like; R 2 and R 3 are each H, alkyl, or the like; m is 0 to 2; and n is 0 or 1.

  该发明提供了新型的唑类化合物，可用作害虫控制剂，以及含有该化合物作为活性成分的新型害虫控制剂。该发明揭示了由以下通式表示的唑类化合物，制备该化合物的生产工艺，并将其用作杀虫剂或螨虫剂：其中X1至X5和Z1至Z4均为N、C—H、C-卤素、C-烷基或类似物；Y1和Y2均为N或CH，但必须满足Y1和Y2不能同时为CH；A为单键、O或类似物；Ar为可选取代的芳香残基；B为卤素、烷基或类似物；R1为H、卤素、烷基或类似物；R2和R3均为H、烷基或类似物；m为0至2；n为0或1。
• AZOLE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF
  申请人：Sumitomo Chemical Takeda Agro Company, Limited

  公开号：EP1386915A1

  公开（公告）日：2004-02-04

  The invention provides novel azole compounds useful as pest controllers and novel pest controllers containing the compounds as the active ingredient. The invention discloses azole compounds represented by the following general formula, a production process for preparation of the compounds, and use thereof as insecticides or acaricides: wherein X1 to X5 and Z1 to Z4 are each N, C-H, C-halogen, C-alkyl, or the like; Y1 and Y2 are each N or CH, with the proviso that both Y1 and Y2 must not be CH; A is a single bond, O, or the like; Ar is an optionally substituted aromatic residue; B is halogeno, alkyl, or the like; R1 is H, halogeno, alkyl, or the like; R2 and R3 are each H, alkyl, or the like; m is 0 to 2; and n is 0 or 1.

  本发明提供了可用作害虫控制剂的新型唑类化合物，以及以该化合物为活性成分的新型害虫控制剂。本发明公开了由以下通式表示的唑类化合物、制备该化合物的生产工艺及其作为杀虫剂或杀螨剂的用途： 其中X1至X5和Z1至Z4各自为N、C-H、C-卤素、C-烷基或类似物；Y1和Y2各自为N或CH，但Y1和Y2均不得为CH；A为单键、O或类似物；Ar为任选取代的芳香残基；B为卤素、烷基或类似物；R1为H、卤素、烷基或类似物；R2和R3各自为H、烷基或类似物；m为0至2；n为0或1。