β,β'-Bis-<2-chlor-4-nitro-phenyloxycarbonyloxy>-aethan | 101762-92-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: β,β'-Bis-<2-chlor-4-nitro-phenyloxycarbonyloxy>-aethan
• 英文别名: 2-[2-(2-Chloro-4-nitrophenoxy)carbonyloxyethoxy]ethyl (2-chloro-4-nitrophenyl) carbonate
• CAS: 101762-92-9
• 化学式: C₁₈H₁₄Cl₂N₂O₁₁
• 分子量: 505.222
• InChiKey: YICCMQOBPQBJOT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  33
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  172
• 氢给体数：
  0
• 氢受体数：
  11

文献信息

• Condensation polymers for antimicrobial applications
  申请人：International Business Machines Corporation

  公开号：US10023697B2

  公开（公告）日：2018-07-17

  A number of cationic antimicrobial polymers have been synthesized by a condensation polymerization in bulk. The initial polymer formed has backbone tertiary nitrogens, which are subsequently quaternized using a suitable quaternizing agent (e.g., alkyl halide). The cationic polymers include polyamides, polycarbonates, polypolyureas and polyguanidiniums having a cationic repeat unit comprising the quaternary ammonium nitrogen as a backbone nitrogen. The cationic polymers can be active against Gram-negative, Gram-positive microbes, and/or fungi.

  许多阳离子抗菌聚合物都是通过缩合聚合反应合成的。最初形成的聚合物具有骨架叔硝基，随后使用适当的季铵化剂（如烷基卤化物）对其进行季铵化。阳离子聚合物包括聚酰胺、聚碳酸酯、聚聚脲和聚胍，其阳离子重复单元包括作为骨架氮的季铵态氮。阳离子聚合物可对革兰氏阴性、革兰氏阳性微生物和/或真菌具有活性。
• CONDENSATION POLYMERS FOR ANTIMICROBIAL APPLICATIONS
  申请人：Agency for Science, Technology and Research

  公开号：EP3292165A1

  公开（公告）日：2018-03-14
• US9580554B2
  申请人：——

  公开号：US9580554B2

  公开（公告）日：2017-02-28
• [EN] CONDENSATION POLYMERS FOR ANTIMICROBIAL APPLICATIONS<br/>[FR] POLYMÈRES DE CONDENSATION POUR APPLICATIONS ANTIMICROBIENNES
  申请人：AGENCY SCIENCE TECH & RES

  公开号：WO2016178634A1

  公开（公告）日：2016-11-10

  The provision of cationic polymers having a cationic repeat unit of formula (I) comprising a positive-charged quarternary ammonium nitrogen as a backbone nitrogen that can be active against Gram -negative, Gram-positive microbes, and/or fungi. The cationic polymers are synthesized by a condensation polymerization in bulk. The initial polymer formed has backbone tertiary nitrogens, which are subsequently quarternized using a suitable quarternizing agent.